This study reports on variations at the mitochondrial DNA (mtDNA) hypervariable region 1 (HVR-1) and at seven Y-chromosome microsatellites in an African-American population sample from Chicago, IL, USA. Our results support the hypothesis that the population studied had undergone a European malebiased gene flow. We show that comparisons of intraand inter-population diversity parameters between African-Americans, Europeans and Africans may help detect sex-biased gene flow, providing a complement to quantitative methods to estimate genetic admixture.

Battaggia, C., Anagnostou, P., Boschi, I., Brisighelli, F., Destro Bisol, G., Capocasa, M., Detecting Sex-Biased Gene Flow in African-Americans through the Analysis of Intra- and Inter-Population Variation at Mitochondrial DNA and Y- Chromosome Microsatellites., <<BALKAN JOURNAL OF MEDICAL GENETICS>>, 2012; (Dicembre): 7-14. [doi:10.2478/bjmg-2013-0001] [http://hdl.handle.net/10807/50454]

Detecting Sex-Biased Gene Flow in African-Americans through the Analysis of Intra- and Inter-Population Variation at Mitochondrial DNA and Y- Chromosome Microsatellites.

Boschi, Ilaria;Brisighelli, Francesca;
2012

Abstract

This study reports on variations at the mitochondrial DNA (mtDNA) hypervariable region 1 (HVR-1) and at seven Y-chromosome microsatellites in an African-American population sample from Chicago, IL, USA. Our results support the hypothesis that the population studied had undergone a European malebiased gene flow. We show that comparisons of intraand inter-population diversity parameters between African-Americans, Europeans and Africans may help detect sex-biased gene flow, providing a complement to quantitative methods to estimate genetic admixture.
Inglese
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776662/
Battaggia, C., Anagnostou, P., Boschi, I., Brisighelli, F., Destro Bisol, G., Capocasa, M., Detecting Sex-Biased Gene Flow in African-Americans through the Analysis of Intra- and Inter-Population Variation at Mitochondrial DNA and Y- Chromosome Microsatellites., <>, 2012; (Dicembre): 7-14. [doi:10.2478/bjmg-2013-0001] [http://hdl.handle.net/10807/50454]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/50454
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