Objective To study the prevalence of congenital syphilis and its risk factors in Italy. Study design Prospective study from 1 July 2006 to 30 June 2007. Data on mother–child pairs were collected for every syphilis seropositive mother. Results Maternal syphilis seroprevalence at delivery was 0.17%. 207 infants were born to 203 syphilis seropositive mothers. In 25 newborns it was possible to diagnose congenital syphilis (20/100 000 live births). Maternal risk factors included age <20 years, no antenatal care and no adequate treatment. The infected babies were more often preterm or weighed <2000 g at birth. Discussion Many syphilis seropositive mothers were foreign born but the risk of an infected newborn was not higher in foreign-born than in Italian seropositive women. The significant factors were lack of antenatal screening and inadequate maternal treatment. Conclusion Syphilis is a re-emerging infection in Italy. Prevention strategies should include antenatal serological tests for all pregnant women and treatment for infected mothers.
Tridapalli, E., Capretti, M., Bacchi Reggiani, M., Stronati, M., Faldella, G., Valentini, P., Et, A., “Congenital syphilis in Italy: multicentre study”., <<ARCHIVES OF DISEASE IN CHILDHOOD>>, 2010; 97 (3): 211-213. [doi:10.1136/adc.2010.183863] [http://hdl.handle.net/10807/43419]
“Congenital syphilis in Italy: multicentre study”.
Valentini, Piero;
2012
Abstract
Objective To study the prevalence of congenital syphilis and its risk factors in Italy. Study design Prospective study from 1 July 2006 to 30 June 2007. Data on mother–child pairs were collected for every syphilis seropositive mother. Results Maternal syphilis seroprevalence at delivery was 0.17%. 207 infants were born to 203 syphilis seropositive mothers. In 25 newborns it was possible to diagnose congenital syphilis (20/100 000 live births). Maternal risk factors included age <20 years, no antenatal care and no adequate treatment. The infected babies were more often preterm or weighed <2000 g at birth. Discussion Many syphilis seropositive mothers were foreign born but the risk of an infected newborn was not higher in foreign-born than in Italian seropositive women. The significant factors were lack of antenatal screening and inadequate maternal treatment. Conclusion Syphilis is a re-emerging infection in Italy. Prevention strategies should include antenatal serological tests for all pregnant women and treatment for infected mothers.
| Campo DC | Valore | Lingua |
|---|---|---|
| dc.authority.academicField2000 | Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA | it |
| dc.authority.ancejournal | ARCHIVES OF DISEASE IN CHILDHOOD | en |
| dc.authority.erc2011 | Microbiology | it |
| dc.authority.people | Tridapalli, E | - |
| dc.authority.people | Capretti, Mg | - |
| dc.authority.people | Bacchi Reggiani, Ml | - |
| dc.authority.people | Stronati, M | - |
| dc.authority.people | Faldella, G | - |
| dc.authority.people | Valentini, Piero | it |
| dc.authority.people | Et,Al | - |
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| dc.contributor.appartenenza.mi | 33186 | * |
| dc.contributor.area | Area 06 - Scienze mediche | * |
| dc.contributor.faculty | FACOLTA' DI MEDICINA E CHIRURGIA "A.GEMELLI" | * |
| dc.contributor.faculty | FACOLTA' DI MEDICINA E CHIRURGIA "A.GEMELLI" | * |
| dc.contributor.faculty | FACOLTA' DI MEDICINA E CHIRURGIA "A.GEMELLI" | * |
| dc.contributor.faculty | FACOLTA' DI MEDICINA E CHIRURGIA "A.GEMELLI" | * |
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| dc.date.accessioned | 2013-04-17T08:20:43Z | - |
| dc.date.available | 2013-04-17T08:20:43Z | - |
| dc.date.issued | 2012 | - |
| dc.description.abstracteng | Objective To study the prevalence of congenital syphilis and its risk factors in Italy. Study design Prospective study from 1 July 2006 to 30 June 2007. Data on mother–child pairs were collected for every syphilis seropositive mother. Results Maternal syphilis seroprevalence at delivery was 0.17%. 207 infants were born to 203 syphilis seropositive mothers. In 25 newborns it was possible to diagnose congenital syphilis (20/100 000 live births). Maternal risk factors included age <20 years, no antenatal care and no adequate treatment. The infected babies were more often preterm or weighed <2000 g at birth. Discussion Many syphilis seropositive mothers were foreign born but the risk of an infected newborn was not higher in foreign-born than in Italian seropositive women. The significant factors were lack of antenatal screening and inadequate maternal treatment. Conclusion Syphilis is a re-emerging infection in Italy. Prevention strategies should include antenatal serological tests for all pregnant women and treatment for infected mothers. | - |
| dc.description.allpeople | Tridapalli, E; Capretti, Mg; Bacchi Reggiani, Ml; Stronati, M; Faldella, G; Valentini, Piero; Et, Al | - |
| dc.description.allpeopleoriginal | Tridapalli, E; Capretti, Mg; Bacchi Reggiani, Ml; Stronati, M; Faldella, G; Valentini, Piero; Et,Al | it |
| dc.description.fulltext | none | en |
| dc.description.fulltextoriginal | none | en |
| dc.description.languageisokeywords | eng | it |
| dc.description.numberofauthors | 7 | - |
| dc.identifier.citation | Tridapalli, E., Capretti, M., Bacchi Reggiani, M., Stronati, M., Faldella, G., Valentini, P., Et, A., “Congenital syphilis in Italy: multicentre study”., <<ARCHIVES OF DISEASE IN CHILDHOOD>>, 2010; 97 (3): 211-213. [doi:10.1136/adc.2010.183863] [http://hdl.handle.net/10807/43419] | it |
| dc.identifier.doi | 10.1136/adc.2010.183863 | - |
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| dc.identifier.uri | http://hdl.handle.net/10807/43419 | - |
| dc.language.iso | eng | it |
| dc.publisher.name | BMJ Publishing Group | it |
| dc.relation.firstpage | 211 | it |
| dc.relation.issue | 3 | - |
| dc.relation.issueyear | 2010 | it |
| dc.relation.lastpage | 213 | it |
| dc.relation.numberofpages | 3 | it |
| dc.relation.volume | 97 | - |
| dc.subject.keywords | syphilis | it |
| dc.subject.keywords | congenital infection | it |
| dc.subject.singlekeyword | syphilis | * |
| dc.title | “Congenital syphilis in Italy: multicentre study”. | it |
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| dc.type.full | 03. Contributo in rivista::Articolo in rivista, Nota a sentenza | it |
| dc.type.genius | Pubblicazione su rivista con Impact Factor | - |
| dc.type.miur | 262 | en |
| dc.type.miurarticle | Articolo in rivista | it |
| dc.type.research | AREA06 - SCIENZE MEDICHE | - |
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| isi.description.allpeopleoriginal | Tridapalli, E; Capretti, MG; Reggiani, MLB; Stronati, M; Faldella, G; | * |
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| isi.journal.journaltitle | ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION | * |
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