Thanks to the recent advances in reproductive medicine, more and more young women with breast cancer may be offered the possibility of preserving their fertility. Fertility can be endangered by chemotherapy, by treatment duration and by patient's age at diagnosis. The currently available means to preserve a young woman's fertility are pharmacological protection with gonadotrophin-releasing hormone analogues during chemotherapy, and ovarian tissue or oocyte/embryo freezing before treatment. New future venues, including in vitro maturation, will improve the feasibility and efficacy of the fertility preservation methods in breast cancer patients.
Peccatori, F., Pup, L., Guido, M., Sarno, M., Salvagno, F., Revelli, A., Piane, L., Dolfin, E., Franchi, D., Molinari, E., Immediata, V., Chiavari, L., Vucetich, A., Borini, A., Fertility Preservation Methods in Breast Cancer, <<BREAST CARE>>, 2012; 7 (3): 197-202. [doi:10.1159/000339671] [http://hdl.handle.net/10807/42301]
Fertility Preservation Methods in Breast Cancer
Guido, Maurizio;
2012
Abstract
Thanks to the recent advances in reproductive medicine, more and more young women with breast cancer may be offered the possibility of preserving their fertility. Fertility can be endangered by chemotherapy, by treatment duration and by patient's age at diagnosis. The currently available means to preserve a young woman's fertility are pharmacological protection with gonadotrophin-releasing hormone analogues during chemotherapy, and ovarian tissue or oocyte/embryo freezing before treatment. New future venues, including in vitro maturation, will improve the feasibility and efficacy of the fertility preservation methods in breast cancer patients.
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