A 40-year-old man was admitted to our hospital for surgical treatment of aortic insufficiency and coronary ostial stenosis. Histopathology and serological tests revealed a syphilitic aortitis. 18F-FDG PET/CTwas performed to assess the extent of aortitis, showing increased radiopharmaceutical uptake along the ascending aortic wall. A repeated FDG PET/CTafter antibiotic therapy showed a markedly reduced uptake in the aortic wall, suggesting resolution of the infection according to clinical and serological data. This case highlights the usefulness of FDG PET/CT for the assessment of disease extent and treatment response in patients with syphilitic aortitis.
Giordano, A., Treglia, G., Taralli, S., Maggi, F., Coli, A., Lauriola, L., Usefulness of 18F-FDG PET/CT in Disease Extent and TreatmentResponse Assessment in a Patient With Syphilitic Aortitis, <<CLINICAL NUCLEAR MEDICINE>>, 2013; (38): 185-197 [http://hdl.handle.net/10807/41981]
Usefulness of 18F-FDG PET/CT in Disease Extent and Treatment Response Assessment in a Patient With Syphilitic Aortitis
Giordano, Alessandro;Treglia, Giorgio;Taralli, Silvia;Coli, Antonella;Lauriola, Libero
2013
Abstract
A 40-year-old man was admitted to our hospital for surgical treatment of aortic insufficiency and coronary ostial stenosis. Histopathology and serological tests revealed a syphilitic aortitis. 18F-FDG PET/CTwas performed to assess the extent of aortitis, showing increased radiopharmaceutical uptake along the ascending aortic wall. A repeated FDG PET/CTafter antibiotic therapy showed a markedly reduced uptake in the aortic wall, suggesting resolution of the infection according to clinical and serological data. This case highlights the usefulness of FDG PET/CT for the assessment of disease extent and treatment response in patients with syphilitic aortitis.
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