The malignant B cells in chronic lymphocytic leukemia receive signals from the bone marrow and lymph node microenvironments which regulate their survival and proliferation. Characterization of these signals and the pathways that propagate them to the interior of the cell is important for the identification of novel potential targets for therapeutic intervention.

De Paula Careta, F., Gobessi, S., Panepucci, R., Bojnik, E., Morato De Oliveira, F., Mazza Matos, D., Falcão, R., Laurenti, L., Zago, M., Efremov, D., The Aurora A and B kinases are up-regulated in bone marrow-derived chronic lymphocytic leukemia cells and represent potential therapeutic targets, <<HAEMATOLOGICA>>, 2012; 97 (8): 1246-1254. [doi:10.3324/haematol.2011.054668] [http://hdl.handle.net/10807/40274]

The Aurora A and B kinases are up-regulated in bone marrow-derived chronic lymphocytic leukemia cells and represent potential therapeutic targets

Laurenti, Luca;
2012

Abstract

The malignant B cells in chronic lymphocytic leukemia receive signals from the bone marrow and lymph node microenvironments which regulate their survival and proliferation. Characterization of these signals and the pathways that propagate them to the interior of the cell is important for the identification of novel potential targets for therapeutic intervention.
2012
Inglese
De Paula Careta, F., Gobessi, S., Panepucci, R., Bojnik, E., Morato De Oliveira, F., Mazza Matos, D., Falcão, R., Laurenti, L., Zago, M., Efremov, D., The Aurora A and B kinases are up-regulated in bone marrow-derived chronic lymphocytic leukemia cells and represent potential therapeutic targets, <<HAEMATOLOGICA>>, 2012; 97 (8): 1246-1254. [doi:10.3324/haematol.2011.054668] [http://hdl.handle.net/10807/40274]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/40274
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