A new, observational study suggests that aspirin only marginally increases the bleeding risk in patients with diabetes mellitus, perhaps reflecting impaired platelet inhibition. Inconclusive evidence from small, randomized trials and mechanistic studies reinforces the need for larger trials to determine the relative cardioprotective benefits and bleeding risks of aspirin in these patients.
Patrono, C., Diabetes: Does aspirin increase the risk of major bleeds?, <<NATURE REVIEWS. CARDIOLOGY>>, 2012; 9 (9): 495-496. [doi:10.1038/nrcardio.2012.113] [http://hdl.handle.net/10807/39885]
Diabetes: Does aspirin increase the risk of major bleeds?
Patrono, Carlo
2012
Abstract
A new, observational study suggests that aspirin only marginally increases the bleeding risk in patients with diabetes mellitus, perhaps reflecting impaired platelet inhibition. Inconclusive evidence from small, randomized trials and mechanistic studies reinforces the need for larger trials to determine the relative cardioprotective benefits and bleeding risks of aspirin in these patients.
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