Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has been evaluated for the identification of multidrug-resistant Acinetobacter baumannii nosocomial outbreaks in comparison with the repetitive sequence-based PCR DiversiLab system. The results suggest that MALDI-TOF MS can be used for real-time detection of Acinetobacter outbreaks before results from DNA-based systems are available.
Mencacci, A., Monari, C., Leli, C., Merlini, L., De Carolis, E., Vella, A., Cacioni, M., Buzi, S., Nardelli, E., Bistoni, F., Sanguinetti, M., Vecchiarelli, A., Typing of Nosocomial Outbreaks of Acinetobacter baumannii by Use of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry, <<JOURNAL OF CLINICAL MICROBIOLOGY>>, 2013; 51 (2): 603-606. [doi:10.1128/JCM.01811-12] [http://hdl.handle.net/10807/39476]
Typing of Nosocomial Outbreaks of Acinetobacter baumannii by Use of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry
De Carolis, Elena;Vella, Antonietta;Sanguinetti, Maurizio;
2013
Abstract
Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has been evaluated for the identification of multidrug-resistant Acinetobacter baumannii nosocomial outbreaks in comparison with the repetitive sequence-based PCR DiversiLab system. The results suggest that MALDI-TOF MS can be used for real-time detection of Acinetobacter outbreaks before results from DNA-based systems are available.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
