In this hospital-based, multicenter case-control study we investigated the prevalence of hepatitis B virus (HBV)-related markers and HBV/hepatitis C virus (HCV) co-infection among B-cell non-Hodgkin’s lymphoma (B-NHL) cases and controls. Four hundred newly diagnosed B-NHL cases and 392 controls from other departments of the same hospitals were studied. The prevalence of positivity for hepatitis B surface antigen (HBsAg) was 8.5% among B-NHL cases and 2.8% among controls (adjusted odds ratio, 3.67; 95% confidence interval, 1.75-7.66). HBV/HCV co-infection was found in four cases, but in no controls. The finding of a positive association between HBV infection and BNHL raises the possibility that HBV may play an etiologic role in the induction of B-NHL.

Marcucci, F., Mele, A., Spada, E., Candido, A., Bianco, E., Pulsoni, A., Chionne, P., Madonna, E., Cotichini, R., Barbui, A., De Renzo, A., Dore, F., Iannitto, E., Liso, V., Martino, B., Montanaro, M., Pagano, L., Musto, P., Rapicetta, M., High prevalence of hepatitis B virus infection in B-cell non-Hodgkin's lymphoma., <<HAEMATOLOGICA>>, 2006; (Maggio): 554-557 [http://hdl.handle.net/10807/3854]

High prevalence of hepatitis B virus infection in B-cell non-Hodgkin's lymphoma.

Pagano, Livio;
2006

Abstract

In this hospital-based, multicenter case-control study we investigated the prevalence of hepatitis B virus (HBV)-related markers and HBV/hepatitis C virus (HCV) co-infection among B-cell non-Hodgkin’s lymphoma (B-NHL) cases and controls. Four hundred newly diagnosed B-NHL cases and 392 controls from other departments of the same hospitals were studied. The prevalence of positivity for hepatitis B surface antigen (HBsAg) was 8.5% among B-NHL cases and 2.8% among controls (adjusted odds ratio, 3.67; 95% confidence interval, 1.75-7.66). HBV/HCV co-infection was found in four cases, but in no controls. The finding of a positive association between HBV infection and BNHL raises the possibility that HBV may play an etiologic role in the induction of B-NHL.
Inglese
Marcucci, F., Mele, A., Spada, E., Candido, A., Bianco, E., Pulsoni, A., Chionne, P., Madonna, E., Cotichini, R., Barbui, A., De Renzo, A., Dore, F., Iannitto, E., Liso, V., Martino, B., Montanaro, M., Pagano, L., Musto, P., Rapicetta, M., High prevalence of hepatitis B virus infection in B-cell non-Hodgkin's lymphoma., <<HAEMATOLOGICA>>, 2006; (Maggio): 554-557 [http://hdl.handle.net/10807/3854]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/3854
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