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EnglishIn this hospital-based, multicenter case-control study we investigated the prevalence of hepatitis B virus (HBV)-related markers and HBV/hepatitis C virus (HCV) co-infection among B-cell non-Hodgkin’s lymphoma (B-NHL) cases and controls. Four hundred newly diagnosed B-NHL cases and 392 controls from other departments of the same hospitals were studied. The prevalence of positivity for hepatitis B surface antigen (HBsAg) was 8.5% among B-NHL cases and 2.8% among controls (adjusted odds ratio, 3.67; 95% confidence interval, 1.75-7.66). HBV/HCV co-infection was found in four cases, but in no controls. The finding of a positive association between HBV infection and BNHL raises the possibility that HBV may play an etiologic role in the induction of B-NHL.
Marcucci, F., Mele, A., Spada, E., Candido, A., Bianco, E., Pulsoni, A., Chionne, P., Madonna, E., Cotichini, R., Barbui, A., De Renzo, A., Dore, F., Iannitto, E., Liso, V., Martino, B., Montanaro, M., Pagano, L., Musto, P., Rapicetta, M., High prevalence of hepatitis B virus infection in B-cell non-Hodgkin's lymphoma., <<HAEMATOLOGICA>>, 2006; (Maggio): 554-557 [http://hdl.handle.net/10807/3854]
| Autori: | ||
| Titolo: | High prevalence of hepatitis B virus infection in B-cell non-Hodgkin's lymphoma. | |
| Data di pubblicazione: | 2006 | |
| Abstract: | In this hospital-based, multicenter case-control study we investigated the prevalence of hepatitis B virus (HBV)-related markers and HBV/hepatitis C virus (HCV) co-infection among B-cell non-Hodgkin’s lymphoma (B-NHL) cases and controls. Four hundred newly diagnosed B-NHL cases and 392 controls from other departments of the same hospitals were studied. The prevalence of positivity for hepatitis B surface antigen (HBsAg) was 8.5% among B-NHL cases and 2.8% among controls (adjusted odds ratio, 3.67; 95% confidence interval, 1.75-7.66). HBV/HCV co-infection was found in four cases, but in no controls. The finding of a positive association between HBV infection and BNHL raises the possibility that HBV may play an etiologic role in the induction of B-NHL. | |
| Lingua: | Inglese | |
| Rivista: | ||
| Citazione: | Marcucci, F., Mele, A., Spada, E., Candido, A., Bianco, E., Pulsoni, A., Chionne, P., Madonna, E., Cotichini, R., Barbui, A., De Renzo, A., Dore, F., Iannitto, E., Liso, V., Martino, B., Montanaro, M., Pagano, L., Musto, P., Rapicetta, M., High prevalence of hepatitis B virus infection in B-cell non-Hodgkin's lymphoma., <<HAEMATOLOGICA>>, 2006; (Maggio): 554-557 [http://hdl.handle.net/10807/3854] | |
| Appare nelle tipologie: | Articolo in rivista, Nota a sentenza |
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