Pontine structures are critical for the generation of rapid eye movement sleep but there are only a few reports of the effects of focal pontine lesions on sleep patterns in humans. We report the case of an 81-year-old man admitted for the acute onset of disordered speech and motor deficit in the upper right arm who developed hypersomnia within a week. A 24-hour polysomnographic study revealed a very severe disruption of both circadian rhythm and sleep organisation, and a brain MRI documented an ischaemic lesion of the anterior left paramedian portion of the pons. Our observation suggests that even small, paramedian pontine ischaemic lesions can acutely induce a very severe sleep disorder.

Tosato, M., Aquila, S., Della Marca, G., Incalzi, R., Gambassi, G., Sleep disruption following paramedian pontine stroke, <<BMJ CASE REPORT>>, 2009; 2009 (Luglio): N/A-N/A. [doi:10.1136/bcr.07.2008.0460] [http://hdl.handle.net/10807/37390]

Sleep disruption following paramedian pontine stroke

Tosato, Matteo;Aquila, Sara;Della Marca, Giacomo;Gambassi, Giovanni
2009

Abstract

Pontine structures are critical for the generation of rapid eye movement sleep but there are only a few reports of the effects of focal pontine lesions on sleep patterns in humans. We report the case of an 81-year-old man admitted for the acute onset of disordered speech and motor deficit in the upper right arm who developed hypersomnia within a week. A 24-hour polysomnographic study revealed a very severe disruption of both circadian rhythm and sleep organisation, and a brain MRI documented an ischaemic lesion of the anterior left paramedian portion of the pons. Our observation suggests that even small, paramedian pontine ischaemic lesions can acutely induce a very severe sleep disorder.
2009
Inglese
Tosato, M., Aquila, S., Della Marca, G., Incalzi, R., Gambassi, G., Sleep disruption following paramedian pontine stroke, <<BMJ CASE REPORT>>, 2009; 2009 (Luglio): N/A-N/A. [doi:10.1136/bcr.07.2008.0460] [http://hdl.handle.net/10807/37390]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/37390
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