We report the case of a 38-year-old woman, affected by a cutaneous form of mycosis fungoides (MF) who presented with a history of loud snoring associated with sleep apnea. A polysomnographic study confirmed the presence of severe obstructive sleep apnea syndrome (OSAS). Cranial and neck MRI revealed a neoplastic infiltration of the tongue base and the posterior pharynx wall. Upper airway neoplastic infiltration is rarely reported as a cause of OSAS and extra-cutaneous localizations of MF are uncommon. This is the first case in the literature of a patient with nocturnal polysomnogram documented OSAS caused by a mucosal involvement of MF.
Luigetti, M., Cianfoni, A., Scarano, E., Laurenti, L., Innocenti, I., Testani, E., Dittoni, S., Della Marca, G., Mycosis fungoides as a cause of severe obstructive sleep apnea, <<INTERNAL MEDICINE>>, 2011; 50 (16): 1753-1755. [doi:10.2169/internalmedicine.50.5541] [http://hdl.handle.net/10807/3658]
Mycosis fungoides as a cause of severe obstructive sleep apnea
Luigetti, Marco;Cianfoni, Alessandro;Scarano, Emanuele;Laurenti, Luca;Innocenti, Idanna;Testani, Elisa;Dittoni, Serena;Della Marca, Giacomo
2011
Abstract
We report the case of a 38-year-old woman, affected by a cutaneous form of mycosis fungoides (MF) who presented with a history of loud snoring associated with sleep apnea. A polysomnographic study confirmed the presence of severe obstructive sleep apnea syndrome (OSAS). Cranial and neck MRI revealed a neoplastic infiltration of the tongue base and the posterior pharynx wall. Upper airway neoplastic infiltration is rarely reported as a cause of OSAS and extra-cutaneous localizations of MF are uncommon. This is the first case in the literature of a patient with nocturnal polysomnogram documented OSAS caused by a mucosal involvement of MF.
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