Objectives: To assess the performance of the power Doppler index (PDI) compared to subjective judgment of the ultrasonographer in the preoperative diagnosis of ovarian malignancy. Methods: Eighty-two successive complex adnexal masses were examined prospectively with power Doppler before surgical treatment. The investigation was multicentric and included in a large contrast-enhanced ultrasound European study. A vascularity index based on the number of colored pixels, was estimated on selected frames (defined region of interest covering the entire tumor) of the tumors using an in-house color quantifying program. The sensitivity and specificity of PDI, the resistance index and subjective visual scoringwere compared using receiver operating characteristic (ROC) curves. Results: Histology identified 34 malignant tumors including 11 borderline tumors and 48 benign tumors. PDI was considerably higher in malignant than in benign lesions: 21.88 (95% CI, 19.19 24.57) vs. 8.11 (95% CI, 6.09 10.19) for the benign tumors and 11.63 (95% CI, 1.20 22.06) for borderline tumors. The PDI cut-off value for differential diagnosis was set at 0.107 (10.7% of the tumor colored). However, the sensitivity and specificity of the PDI were quite low: 75% (95% CI, 72.9 90.7) and 60% (95% CI, 56.3 92.5) respectively. Using logistic regression, visual Doppler scoring alone (OR 6.14 (95% CI, 2.30 16.38), P = 0.0003) or associated with gray-scale examination (OR 10.5 (95% CI, 3.19 34.54), P = 0.0001) performed better than PDI (OR 2.61 (95% CI, 1.06 6.43), P = 0.04). Conclusions: The power Doppler index obtained using our color quantifying software has discriminating power for adnexal masses, but visual Doppler scoring performed best.

Marret, H., Vinatier, L., Giradeau, B., Tranquart, F., Testa, A. C., Igit Study, G., Ultrasonographer experience vs. power Doppler index for ovarian tumor discrimination, Abstract de <<17th World Congress on Ultrasoundin Obstetrics and Gynecology>>, (Firenze, 07-11 October 2007 ), <<ULTRASOUND IN OBSTETRICS & GYNECOLOGY>>, 2007; 2007 (Ottobre): 431-431 [http://hdl.handle.net/10807/35521]

Ultrasonographer experience vs. power Doppler index for ovarian tumor discrimination

F; Testa;
2007

Abstract

Objectives: To assess the performance of the power Doppler index (PDI) compared to subjective judgment of the ultrasonographer in the preoperative diagnosis of ovarian malignancy. Methods: Eighty-two successive complex adnexal masses were examined prospectively with power Doppler before surgical treatment. The investigation was multicentric and included in a large contrast-enhanced ultrasound European study. A vascularity index based on the number of colored pixels, was estimated on selected frames (defined region of interest covering the entire tumor) of the tumors using an in-house color quantifying program. The sensitivity and specificity of PDI, the resistance index and subjective visual scoringwere compared using receiver operating characteristic (ROC) curves. Results: Histology identified 34 malignant tumors including 11 borderline tumors and 48 benign tumors. PDI was considerably higher in malignant than in benign lesions: 21.88 (95% CI, 19.19 24.57) vs. 8.11 (95% CI, 6.09 10.19) for the benign tumors and 11.63 (95% CI, 1.20 22.06) for borderline tumors. The PDI cut-off value for differential diagnosis was set at 0.107 (10.7% of the tumor colored). However, the sensitivity and specificity of the PDI were quite low: 75% (95% CI, 72.9 90.7) and 60% (95% CI, 56.3 92.5) respectively. Using logistic regression, visual Doppler scoring alone (OR 6.14 (95% CI, 2.30 16.38), P = 0.0003) or associated with gray-scale examination (OR 10.5 (95% CI, 3.19 34.54), P = 0.0001) performed better than PDI (OR 2.61 (95% CI, 1.06 6.43), P = 0.04). Conclusions: The power Doppler index obtained using our color quantifying software has discriminating power for adnexal masses, but visual Doppler scoring performed best.
Inglese
Marret, H., Vinatier, L., Giradeau, B., Tranquart, F., Testa, A. C., Igit Study, G., Ultrasonographer experience vs. power Doppler index for ovarian tumor discrimination, Abstract de <<17th World Congress on Ultrasoundin Obstetrics and Gynecology>>, (Firenze, 07-11 October 2007 ), <<ULTRASOUND IN OBSTETRICS & GYNECOLOGY>>, 2007; 2007 (Ottobre): 431-431 [http://hdl.handle.net/10807/35521]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/35521
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