The frequency of primary clarithromycin resistance in Helicobacter pylori strains is increasing worldwide, and its presence significantly reduces the treatment efficacy of infection. This study aimed to evaluate whether the progression of the prevalence of clarithromycin resistance over a 15 year period has increased and whether a possible change in the distribution of the three most frequent point mutations, which account for the large majority of clarithromycin resistance cases, has taken place.

De Francesco, V., Margiotta, M., Zullo, A., Hassan, C., Giorgio, F., Burattini, O., Stoppino, G., Cea, U., Pace, A., Zotti, M., Morini, S., Panella, C., Ierardi, E., Prevalence of primary clarithromycin resistance in Helicobacter pylori strains over a 15 year period in Italy, <<JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY>>, N/A; 59 (4): 783-785. [doi:10.1093/jac/dkm005] [http://hdl.handle.net/10807/34767]

Prevalence of primary clarithromycin resistance in Helicobacter pylori strains over a 15 year period in Italy

Hassan, Cesare;
2007

Abstract

The frequency of primary clarithromycin resistance in Helicobacter pylori strains is increasing worldwide, and its presence significantly reduces the treatment efficacy of infection. This study aimed to evaluate whether the progression of the prevalence of clarithromycin resistance over a 15 year period has increased and whether a possible change in the distribution of the three most frequent point mutations, which account for the large majority of clarithromycin resistance cases, has taken place.
2007
Inglese
De Francesco, V., Margiotta, M., Zullo, A., Hassan, C., Giorgio, F., Burattini, O., Stoppino, G., Cea, U., Pace, A., Zotti, M., Morini, S., Panella, C., Ierardi, E., Prevalence of primary clarithromycin resistance in Helicobacter pylori strains over a 15 year period in Italy, <<JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY>>, N/A; 59 (4): 783-785. [doi:10.1093/jac/dkm005] [http://hdl.handle.net/10807/34767]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/34767
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