En-bloc resection of bladder tumors for pathological staging: the value of lateral margins analysis

BacKgroUND: in endoscopic resection of colorectal tumors, the pathological assessment of the lateral margins is a strong predictor of tumor recurrence after resection. The aim of the current study is to evaluate the value of the peritumoral margins assessment in erBT on tumor recurrence. MeTHoDS: We retrospectively analyzed the data of 50 consecutive patients with NMiBc and treated by erBT between January and December 2017. reSUlTS: The lateral margins showed dysplasia in 16 patients and malignancy in three patients. local recurrence occurred in 14 (28%) patients. it was noted that 57% of patients with recurrence showed some degree of dysplasia or malignancy in the lateral margin; however, on multivariate logistic regression lateral margins lesions were not significantly associated with recurrence (or 2.175, 95% ci: 0.430-10.996, P=0.35). coNclUSioNS: erBT may improve the pathological report of bladder tumor. There was a trend toward increased rate of recurrence in patients with dysplasia or malignancy in their lateral margins; however, this was not statistically significant on multivariate analysis. Further studies with larger sample sizes are required to assess the value of lateral margin analysis.