Azathioprine therapy is discontinued in one-third of patients with inflammatory bowel disease because of toxicity or a lack of clinical response. Patients with thiopurine methyltransferase (TPMT) deficiency are intolerant to azathioprine, whilst carriers are at increased risk of side-effects.

Ansari, A., Hassan, C., Duley, J., Marinaki, A., Shobowale Bakre, E., Seed, P., Meenan, J., Yim, A., Sanderson, J., Thiopurine methyltransferase activity and the use of azathioprine in inflammatory bowel disease, <<ALIMENTARY PHARMACOLOGY & THERAPEUTICS>>, N/A; 16 (10): 1743-1750 [http://hdl.handle.net/10807/34633]

Thiopurine methyltransferase activity and the use of azathioprine in inflammatory bowel disease

Hassan, Cesare;
2002

Abstract

Azathioprine therapy is discontinued in one-third of patients with inflammatory bowel disease because of toxicity or a lack of clinical response. Patients with thiopurine methyltransferase (TPMT) deficiency are intolerant to azathioprine, whilst carriers are at increased risk of side-effects.
2002
Inglese
Ansari, A., Hassan, C., Duley, J., Marinaki, A., Shobowale Bakre, E., Seed, P., Meenan, J., Yim, A., Sanderson, J., Thiopurine methyltransferase activity and the use of azathioprine in inflammatory bowel disease, <<ALIMENTARY PHARMACOLOGY & THERAPEUTICS>>, N/A; 16 (10): 1743-1750 [http://hdl.handle.net/10807/34633]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/34633
Citazioni
  • ???jsp.display-item.citation.pmc??? 41
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact