We measured α-Klotho in CSF and serum of PD patients at early stage of the disease, finding two distinct pools, the first increased, the second reduced. CSF α-Klotho was inversely associated with CSF α-synuclein levels. Our preliminary results suggest α-Klotho as potential biomarker or therapeutic target in PD.

Sancesario, G. M., Di Lazzaro, G., Grillo, P., Biticchi, B., Giannella, E., Alwardat, M., Pieri, M., Bernardini, S., Mercuri, N. B., Pisani, A., Schirinzi, T., Biofluids profile of α-Klotho in patients with Parkinson's disease, <<PARKINSONISM & RELATED DISORDERS>>, 2021; 90 (NA): 62-64. [doi:10.1016/j.parkreldis.2021.08.004] [https://hdl.handle.net/10807/328782]

Biofluids profile of α-Klotho in patients with Parkinson's disease

Di Lazzaro, Giulia;
2021

Abstract

We measured α-Klotho in CSF and serum of PD patients at early stage of the disease, finding two distinct pools, the first increased, the second reduced. CSF α-Klotho was inversely associated with CSF α-synuclein levels. Our preliminary results suggest α-Klotho as potential biomarker or therapeutic target in PD.
2021
Inglese
Sancesario, G. M., Di Lazzaro, G., Grillo, P., Biticchi, B., Giannella, E., Alwardat, M., Pieri, M., Bernardini, S., Mercuri, N. B., Pisani, A., Schirinzi, T., Biofluids profile of α-Klotho in patients with Parkinson's disease, <<PARKINSONISM & RELATED DISORDERS>>, 2021; 90 (NA): 62-64. [doi:10.1016/j.parkreldis.2021.08.004] [https://hdl.handle.net/10807/328782]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/328782
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