To report the feasibility of volumetric modulated arc therapy (VMAT) for neoadjuvant radiotherapy in locally advanced rectal cancer in a dose-escalation protocol and simultaneous integrated boost (SIB) approach. Moreover, the VMAT technique was compared with three-dimensional conformal radiotherapy (3D-CRT) and fixed-field intensity modulated radiotherapy (IMRT), in terms of target coverage and irradiation of organs at risk.
Cilla, S., Caravatta, L., Picardi, V., Sabatino, D., Macchia, G., Digesu', C., Deodato, F., Massaccesi, M., De Spirito, M., Piermattei, A., Morganti, A. G., Volumetric modulated arc therapy with simultaneous integrated boost for locally advanced rectal cancer, <<CLINICAL ONCOLOGY>>, 2012; 24 (4): 261-268. [doi:10.1016/j.clon.2011.07.001] [http://hdl.handle.net/10807/32864]
Volumetric modulated arc therapy with simultaneous integrated boost for locally advanced rectal cancer
Cilla, Savino;Caravatta, Luciana;Picardi, Vincenzo;Sabatino, Domenico;Macchia, Gabriella;Digesu', Cinzia;Deodato, Francesco;Massaccesi, Mariangela;De Spirito, Marco;Piermattei, Angelo;Morganti, Alessio Giuseppe
2012
Abstract
To report the feasibility of volumetric modulated arc therapy (VMAT) for neoadjuvant radiotherapy in locally advanced rectal cancer in a dose-escalation protocol and simultaneous integrated boost (SIB) approach. Moreover, the VMAT technique was compared with three-dimensional conformal radiotherapy (3D-CRT) and fixed-field intensity modulated radiotherapy (IMRT), in terms of target coverage and irradiation of organs at risk.
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