Observational studies suggest that bariatric-metabolic surgery might greatly improve non-alcoholic steatohepatitis (NASH). However, the efficacy of surgery on NASH has not yet been compared with the effects of lifestyle interventions and medical therapy in a randomised trial.
Verrastro, O., Panunzi, S., Castagneto-Gissey, L., De Gaetano, A., Lembo, E., Capristo, E., Guidone, C., Angelini, G., Pennestrì, F., Sessa, L., Vecchio, F. M., Riccardi, L., Zocco, M. A., Boskoski, I., R Casella-Mariolo, J., Marini, P., Pompili, M., Casella, G., Fiori, E., Rubino, F., R Bornstein, S., Raffaelli, M., Mingrone, G., Bariatric-metabolic surgery versus lifestyle intervention plus best medical care in non-alcoholic steatohepatitis (BRAVES): a multicentre, open-label, randomised trial, <<THE LANCET>>, 2023; 401 (10390): 1786-1797. [doi:10.1016/S0140-6736(23)00634-7] [https://hdl.handle.net/10807/322076]
Bariatric-metabolic surgery versus lifestyle intervention plus best medical care in non-alcoholic steatohepatitis (BRAVES): a multicentre, open-label, randomised trial
Verrastro, Ornella;Panunzi, Simona;Lembo, Erminia;Capristo, Esmeralda;Guidone, Caterina;Angelini, Giulia;Sessa, Luca;Vecchio, Fabio Maria;Riccardi, Laura;Zocco, Maria Assunta;Boskoski, Ivo;Pompili, Maurizio;Casella, Giovanni;Raffaelli, Marco;Mingrone, Geltrude
2023
Abstract
Observational studies suggest that bariatric-metabolic surgery might greatly improve non-alcoholic steatohepatitis (NASH). However, the efficacy of surgery on NASH has not yet been compared with the effects of lifestyle interventions and medical therapy in a randomised trial.
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