In this case–control study, consecutive patients with a diagnosis of migraine according to ICHD-3 criteria were included, and tear fluid was collected from migraine patients and HCs. Clinical characteristics of migraine patients, including monthly headache days (MHDs), were recorded. The ictal phase was defined as the presence of a headache with migraine features (not lasting >24 hours).
Romozzi, M., Nardo, L. D., Trigila, V., Cuffaro, G., Savino, G., Iannone, L. F., Rizzo, S., Vollono, C., Calabresi, P., CGRP increase in tear fluid of migraine patients is reversed by anti-CGRP monoclonal antibodies, <<JOURNAL OF NEUROLOGY, NEUROSURGERY AND PSYCHIATRY>>, 2025; (N/A): N/A-N/A. [doi:10.1136/jnnp-2025-335868] [https://hdl.handle.net/10807/318678]
CGRP increase in tear fluid of migraine patients is reversed by anti-CGRP monoclonal antibodies
Romozzi, Marina;Cuffaro, Giovanni;Savino, Gustavo;Rizzo, Stanislao;Vollono, Catello;Calabresi, Paolo
2025
Abstract
In this case–control study, consecutive patients with a diagnosis of migraine according to ICHD-3 criteria were included, and tear fluid was collected from migraine patients and HCs. Clinical characteristics of migraine patients, including monthly headache days (MHDs), were recorded. The ictal phase was defined as the presence of a headache with migraine features (not lasting >24 hours).
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