Deep Brain Stimulation (DBS) is a clinically suitable technique for the treatment of the Parkinson's disease. Recently, also other neurological disorders such as Tourette syndrome, obsessive-compulsive disorder, epilepsy are being to be treated with DBS. However, the debate on its therapeutic mechanisms of action is still open. In order to a better understanding of such mechanisms, in this work the attention is focused on the DBS micro-stimulation. Indeed, a micro electrodes registration and stimulation is a fundamental step, during the surgical phase, to optimize the technique in terms of DBS lead positioning and DBS signal parameters. In this paper a dosimetric analysis with micro electrodes has been carried out, showing a more focused distribution of the electrical potential induced in the neuroanatomical tissues and changes of the excited/inhibited regions, respect to a macro electrodes stimulation. © 2010 IEEE.
Maggio, F., Pasciuto, T., Paffi, A., Apollonio, F., Parazzini, M., Ravazzani, P., D'Inzeo, G., Micro vs macro electrode DBS stimulation: A dosimetric study, (Buenos Aires, 30-August 04-September 2010), <<Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference>>, 2010; 2010 (n/a): 2057-2060.[doi: 10.1109/IEMBS.2010.5626487] [https://hdl.handle.net/10807/317382]
Micro vs macro electrode DBS stimulation: A dosimetric study
Pasciuto, Tina;
2010
Abstract
Deep Brain Stimulation (DBS) is a clinically suitable technique for the treatment of the Parkinson's disease. Recently, also other neurological disorders such as Tourette syndrome, obsessive-compulsive disorder, epilepsy are being to be treated with DBS. However, the debate on its therapeutic mechanisms of action is still open. In order to a better understanding of such mechanisms, in this work the attention is focused on the DBS micro-stimulation. Indeed, a micro electrodes registration and stimulation is a fundamental step, during the surgical phase, to optimize the technique in terms of DBS lead positioning and DBS signal parameters. In this paper a dosimetric analysis with micro electrodes has been carried out, showing a more focused distribution of the electrical potential induced in the neuroanatomical tissues and changes of the excited/inhibited regions, respect to a macro electrodes stimulation. © 2010 IEEE.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
