COVID-19 vaccination recommendations include healthcare workers (HCWs). We measured COVID-19 vaccine effectiveness (CVE) of the autumn 2023 dose against laboratory-confirmed SARS-CoV-2 infection in a prospective cohort study of 1,305 HCWs from 13 European hospitals. Overall CVE was 22% (95% CI: -17 to 48), 49% (95% CI: -8 to 76) before and -11% (95% CI: -84 to 34) after the start of BA.2.86/JN.1 predominant circulation. Autumn 2023 COVID-19 vaccination led to a moderate-to-low reduction in SARS-CoV-2 infection incidence in HCWs. Monitoring of CVE is crucial for COVID-19 prevention.

Savulescu, C., Prats-Uribe, A., Brolin, K., Uusküla, A., Bergin, C., Fleming, C., Murri, R., Zvirbulis, V., Zavadska, D., Gaio, V., Popescu, C. P., Hrisca, R., Cisneros, M., Latorre-Millán, M., Lohur, L., Mcgrath, J., Ferguson, L., De Gaetano Donati, K., Abolina, I., Gravele, D., Machado, A., Florescu, S., Lazar, M., Subirats, P., Clusa Cuesta, L., Sui, J., Kenny, C., Santangelo, R., Krievins, D., Barzdina, E. A., Valadas Henriques, C., Kosa, A. G., Pohrib, S., Muñoz-Almagro, C., Milagro, A., Bacci, S., Nardone, A., Effectiveness of the autumn 2023 COVID-19 vaccine dose in hospital-based healthcare workers: results of the VEBIS healthcare worker vaccine effectiveness cohort study, seven European countries, season 2023/24, <<EUROSURVEILLANCE>>, 2024; 29 (44): N/A-N/A. [doi:10.2807/1560-7917.ES.2024.29.44.2400680] [https://hdl.handle.net/10807/316877]

Effectiveness of the autumn 2023 COVID-19 vaccine dose in hospital-based healthcare workers: results of the VEBIS healthcare worker vaccine effectiveness cohort study, seven European countries, season 2023/24

Murri, Rita;De Gaetano Donati, Katleen;Santangelo, Rosaria;
2024

Abstract

COVID-19 vaccination recommendations include healthcare workers (HCWs). We measured COVID-19 vaccine effectiveness (CVE) of the autumn 2023 dose against laboratory-confirmed SARS-CoV-2 infection in a prospective cohort study of 1,305 HCWs from 13 European hospitals. Overall CVE was 22% (95% CI: -17 to 48), 49% (95% CI: -8 to 76) before and -11% (95% CI: -84 to 34) after the start of BA.2.86/JN.1 predominant circulation. Autumn 2023 COVID-19 vaccination led to a moderate-to-low reduction in SARS-CoV-2 infection incidence in HCWs. Monitoring of CVE is crucial for COVID-19 prevention.
2024
Inglese
Savulescu, C., Prats-Uribe, A., Brolin, K., Uusküla, A., Bergin, C., Fleming, C., Murri, R., Zvirbulis, V., Zavadska, D., Gaio, V., Popescu, C. P., Hrisca, R., Cisneros, M., Latorre-Millán, M., Lohur, L., Mcgrath, J., Ferguson, L., De Gaetano Donati, K., Abolina, I., Gravele, D., Machado, A., Florescu, S., Lazar, M., Subirats, P., Clusa Cuesta, L., Sui, J., Kenny, C., Santangelo, R., Krievins, D., Barzdina, E. A., Valadas Henriques, C., Kosa, A. G., Pohrib, S., Muñoz-Almagro, C., Milagro, A., Bacci, S., Nardone, A., Effectiveness of the autumn 2023 COVID-19 vaccine dose in hospital-based healthcare workers: results of the VEBIS healthcare worker vaccine effectiveness cohort study, seven European countries, season 2023/24, <<EUROSURVEILLANCE>>, 2024; 29 (44): N/A-N/A. [doi:10.2807/1560-7917.ES.2024.29.44.2400680] [https://hdl.handle.net/10807/316877]
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