Crohn's disease (CD) is a chronic inflammatory disease associated with a significant burden in terms of quality of life and health care costs. It is frequently associated with several complications, including the development of intestinal strictures. Stricturing CD requires a careful multidisciplinary approach involving medical therapy and surgery, still posing a continuous management challenge; in this context, endoscopic treatment represents a valuable, in-between opportunity as a minimally invasive strategy endorsed by extensive yet heterogeneous evidence and evolving research and techniques. This review summarizes current knowledge on the role of therapeutic endoscopy in stricturing CD, focusing on evidence gaps, recent updates, and novel techniques intended for optimizing efficacy, safety, and tailoring of this approach in the view of precision endoscopy.

Coppola, G., Principessa, C., Di Vincenzo, F., Puca, P., Del Gaudio, A., Capobianco, I., Bartocci, B., Papa, A., Cammarota, G., Lopetuso, L. R., Scaldaferri, F., Endoscopic Management of Strictures in Crohn’s Disease: An Unsolved Case, <<JOURNAL OF CLINICAL MEDICINE>>, 2024; 13 (16): N/A-N/A. [doi:10.3390/jcm13164842] [https://hdl.handle.net/10807/306540]

Endoscopic Management of Strictures in Crohn’s Disease: An Unsolved Case

Di Vincenzo, Federica;Puca, Pierluigi;Del Gaudio, Angelo;Capobianco, Ivan;Bartocci, Bianca;Papa, Alfredo
Conceptualization
;
Cammarota, Giovanni;Lopetuso, Loris Riccardo;Scaldaferri, Franco
2024

Abstract

Crohn's disease (CD) is a chronic inflammatory disease associated with a significant burden in terms of quality of life and health care costs. It is frequently associated with several complications, including the development of intestinal strictures. Stricturing CD requires a careful multidisciplinary approach involving medical therapy and surgery, still posing a continuous management challenge; in this context, endoscopic treatment represents a valuable, in-between opportunity as a minimally invasive strategy endorsed by extensive yet heterogeneous evidence and evolving research and techniques. This review summarizes current knowledge on the role of therapeutic endoscopy in stricturing CD, focusing on evidence gaps, recent updates, and novel techniques intended for optimizing efficacy, safety, and tailoring of this approach in the view of precision endoscopy.
2024
Inglese
Coppola, G., Principessa, C., Di Vincenzo, F., Puca, P., Del Gaudio, A., Capobianco, I., Bartocci, B., Papa, A., Cammarota, G., Lopetuso, L. R., Scaldaferri, F., Endoscopic Management of Strictures in Crohn’s Disease: An Unsolved Case, <<JOURNAL OF CLINICAL MEDICINE>>, 2024; 13 (16): N/A-N/A. [doi:10.3390/jcm13164842] [https://hdl.handle.net/10807/306540]
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