A 61-year-old man underwent splenopancreasectomy for a 3-cm neuroendocrine tumor of the body of the pancreas (G2, pT1 pN0, Ki67 3%). Five months after surgery 68Ga-DOTATOC PET/CT showed increased radiotracer uptake in a solid tissue of the splenic fossa, possibly referring to a splenosis nodule. After 19 months, a further 68Ga-DOTATOC PET/CT showed a significant functional and dimensional increase of the previously detected tissue and the appearance of a new finding in the left lateral abdominal wall. In the suspicion of neuroendocrine tumor relapse, the patient underwent surgical excision of the documented lesions. Histology showed splenosis in both nodules.
Guarneri, A., Rufini, V., Schinzari, G., Rindi, G., Leccisotti, L., Atypical Presentation of Splenic Tissue Mimicking Neuroendocrine Tumor Relapse, <<CLINICAL NUCLEAR MEDICINE>>, 2024; 49 (10): e509-e510. [doi:10.1097/RLU.0000000000005349] [https://hdl.handle.net/10807/298318]
Atypical Presentation of Splenic Tissue Mimicking Neuroendocrine Tumor Relapse
Rufini, Vittoria
;Schinzari, Giovanni;Rindi, Guido;Leccisotti, Lucia
2024
Abstract
A 61-year-old man underwent splenopancreasectomy for a 3-cm neuroendocrine tumor of the body of the pancreas (G2, pT1 pN0, Ki67 3%). Five months after surgery 68Ga-DOTATOC PET/CT showed increased radiotracer uptake in a solid tissue of the splenic fossa, possibly referring to a splenosis nodule. After 19 months, a further 68Ga-DOTATOC PET/CT showed a significant functional and dimensional increase of the previously detected tissue and the appearance of a new finding in the left lateral abdominal wall. In the suspicion of neuroendocrine tumor relapse, the patient underwent surgical excision of the documented lesions. Histology showed splenosis in both nodules.
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