Lhermitte-Duclos disease (LDD) is a rare benign lesion of uncertain pathogenesis characterised by distortion of the normal cerebellar laminar cytoarchitecture. We report a case of LDD thoroughly characterized by advanced magnetic resonance imaging techniques, with diffusion-weighted, perfusion-weighted and post-gadolinium sequences. Imaging showed restricted diffusion consistent with high cellularity, high degree of vascularity and preserved blood-brain barrier permeability, correlating with pathology.
Cianfoni, A., Wintermark, M., Piludu, F., D'Alessandris, Q. G., Lauriola, L., Visocchi, M., Colosimo, C., Morphological and functional mr imaging of lhermitte-duclos disease with pathology correlate., <<JOURNAL OF NEURORADIOLOGY>>, 2008; 35 (5): 297-300. [doi:10.1016/j.neurad.2008.05.002] [http://hdl.handle.net/10807/29202]
Morphological and functional mr imaging of lhermitte-duclos disease with pathology correlate.
Cianfoni, Alessandro;Piludu, Francesca;D'Alessandris, Quintino Giorgio;Lauriola, Libero;Visocchi, Massimiliano;Colosimo, Cesare
2008
Abstract
Lhermitte-Duclos disease (LDD) is a rare benign lesion of uncertain pathogenesis characterised by distortion of the normal cerebellar laminar cytoarchitecture. We report a case of LDD thoroughly characterized by advanced magnetic resonance imaging techniques, with diffusion-weighted, perfusion-weighted and post-gadolinium sequences. Imaging showed restricted diffusion consistent with high cellularity, high degree of vascularity and preserved blood-brain barrier permeability, correlating with pathology.
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