It has long been suggested that infectious agents may trigger sarcoidosis through their infectious or antigenic properties. A patient with airway colonization from P. aeruginosa in the setting of idiopathic bronchiolitis (IB) mimicking diffuse panbronchiolitis (DPB) developed sarcoidosis. Impressive clinical and radiological improvement of both bronchiolitis and sarcoidosis features was achieved with a one-year treatment with low-dose erythromycin, thus suggesting a possible link between the two conditions in this specific case. Pathogenic hypotheses and therapeutic implications are specifically discussed.
Trisolini, R., Cancellieri, A., Paioli, D., Burzi, M., Orlandi, P., Patelli, M., Sarcoidosis in the setting of idiopathic chronic bronchiolitis with airway colonization from P. aeruginosa: treatment with low-dose macrolides, <<INTERNAL MEDICINE>>, 2008; 47 (6): 537-542. [doi:10.2169/internalmedicine.47.0675] [https://hdl.handle.net/10807/282190]
Sarcoidosis in the setting of idiopathic chronic bronchiolitis with airway colonization from P. aeruginosa: treatment with low-dose macrolides
Trisolini, RoccoPrimo
;Cancellieri, Alessandra;Paioli, Daniela;
2008
Abstract
It has long been suggested that infectious agents may trigger sarcoidosis through their infectious or antigenic properties. A patient with airway colonization from P. aeruginosa in the setting of idiopathic bronchiolitis (IB) mimicking diffuse panbronchiolitis (DPB) developed sarcoidosis. Impressive clinical and radiological improvement of both bronchiolitis and sarcoidosis features was achieved with a one-year treatment with low-dose erythromycin, thus suggesting a possible link between the two conditions in this specific case. Pathogenic hypotheses and therapeutic implications are specifically discussed.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.