BackgroundRenal cell carcinoma accounts for 2-3% of all malignant cancers in adults and is characterized by the potential development of venous tumor thrombus.Case presentationWe present a rare case of a 62-year-old Caucasian man who arrived in the emergency department for monosymptomatic hematuria. Further investigation revealed a right renal cell carcinoma with 16 cm intravascular extension through the renal vein into the inferior vena cava and right atrium associated with significant coronary artery disease based on the computed tomography scan and coronary angiography. To the best of our knowledge, after an extensive literature review, only one similar case has been reported with involvement of the contralateral kidney. Therefore, there are no applicable management recommendations. After performing coronary artery bypass graft surgery, we proceeded with an open right radical nephrectomy and inferior vena cava and right atrium thrombectomy under cardiopulmonary bypass and while the patient's heart was still beating. The postoperative course went without complications, and the patient was discharged from the hospital on the 10th postoperative day.ConclusionsRadical nephrectomy and thrombectomy with reconstruction of the inferior vena cava combined with coronary artery bypass graft can be performed safely and effectively in selected patients with renal cell carcinoma and significant coronary artery disease. Multidisciplinary teamwork and careful patient selection are essential for optimal outcomes.

Filomena, G. B., Marino, F., Scarciglia, E., Russo, P., Fantasia, F., Bientinesi, R., Ragonese, M., Foschi, N., Gulino, G., Sacco, E., Racioppi, M., Simultaneous surgical management of renal cancer with atrial thrombotic extension and severe chronic coronary artery disease: a case report, <<JOURNAL OF MEDICAL CASE REPORTS>>, 2023; 17 (1): 543-546. [doi:10.1186/s13256-023-04292-3] [https://hdl.handle.net/10807/279636]

Simultaneous surgical management of renal cancer with atrial thrombotic extension and severe chronic coronary artery disease: a case report

Filomena, Giovanni Battista
Primo
Writing – Original Draft Preparation
;
Marino, Filippo
Secondo
Writing – Original Draft Preparation
;
Scarciglia, Eros
Supervision
;
Russo, Pierluigi
Supervision
;
Fantasia, Fabrizio
Resources
;
Bientinesi, Riccardo
Resources
;
Ragonese, Mauro
Writing – Review & Editing
;
Foschi, Nazario
Resources
;
Gulino, Gaetano
Resources
;
Sacco, Emilio
Supervision
;
Racioppi, Marco
Conceptualization
2023

Abstract

BackgroundRenal cell carcinoma accounts for 2-3% of all malignant cancers in adults and is characterized by the potential development of venous tumor thrombus.Case presentationWe present a rare case of a 62-year-old Caucasian man who arrived in the emergency department for monosymptomatic hematuria. Further investigation revealed a right renal cell carcinoma with 16 cm intravascular extension through the renal vein into the inferior vena cava and right atrium associated with significant coronary artery disease based on the computed tomography scan and coronary angiography. To the best of our knowledge, after an extensive literature review, only one similar case has been reported with involvement of the contralateral kidney. Therefore, there are no applicable management recommendations. After performing coronary artery bypass graft surgery, we proceeded with an open right radical nephrectomy and inferior vena cava and right atrium thrombectomy under cardiopulmonary bypass and while the patient's heart was still beating. The postoperative course went without complications, and the patient was discharged from the hospital on the 10th postoperative day.ConclusionsRadical nephrectomy and thrombectomy with reconstruction of the inferior vena cava combined with coronary artery bypass graft can be performed safely and effectively in selected patients with renal cell carcinoma and significant coronary artery disease. Multidisciplinary teamwork and careful patient selection are essential for optimal outcomes.
2023
Inglese
Filomena, G. B., Marino, F., Scarciglia, E., Russo, P., Fantasia, F., Bientinesi, R., Ragonese, M., Foschi, N., Gulino, G., Sacco, E., Racioppi, M., Simultaneous surgical management of renal cancer with atrial thrombotic extension and severe chronic coronary artery disease: a case report, <<JOURNAL OF MEDICAL CASE REPORTS>>, 2023; 17 (1): 543-546. [doi:10.1186/s13256-023-04292-3] [https://hdl.handle.net/10807/279636]
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