Sarcopenia is a complex multifactorial condition that can by treated with multimodal approaches. No pharmacologic agent to prevent or treat sarcopenia has been as efficacious as exercise (mainly resistance training) in combination with nutritional intervention (adequate protein and energy intake). However, performing resistance training sessions and following nutritional advice can be challenging, especially for frail, sarcopenic, elderly patients, and results remain only partial. Therefore, new pharmacologic agents may substantially reduce the functional decline in older people. This article reviews the new pharmacologic agents currently being assessed for treating sarcopenia.
Rolland, Y., Onder, G., Morley, J., Gillette Guyonet, S., Abellan Van Kan, G., Vellas, B., Current and future pharmacologic treatment of sarcopenia, <<CLINICS IN GERIATRIC MEDICINE>>, 2011; 27 (3): 423-447. [doi:10.1016/j.cger.2011.03.008] [http://hdl.handle.net/10807/27419]
Current and future pharmacologic treatment of sarcopenia
Onder, Graziano;
2011
Abstract
Sarcopenia is a complex multifactorial condition that can by treated with multimodal approaches. No pharmacologic agent to prevent or treat sarcopenia has been as efficacious as exercise (mainly resistance training) in combination with nutritional intervention (adequate protein and energy intake). However, performing resistance training sessions and following nutritional advice can be challenging, especially for frail, sarcopenic, elderly patients, and results remain only partial. Therefore, new pharmacologic agents may substantially reduce the functional decline in older people. This article reviews the new pharmacologic agents currently being assessed for treating sarcopenia.
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