Reduced renal function increases the risk of adverse drug reactions (ADRs) to hydrosoluble drugs (hADRs). However, the ability of different equations to calculate estimated glomerular filtration rate (eGFR) or estimated creatinine clearance (eCCr) and thereby predict the risk of developing hADRs has not previously been compared.
Corsonello, A., Pedone, C., Lattanzio, F., Onder, G., Antonelli Incalzi, R., Association between glomerular filtration rate and adverse drug reactions in elderly hospitalized patients: the role of the estimating equation, <<DRUGS & AGING>>, 2011; 28 (5): 379-390. [doi:10.2165/11588280-000000000-00000] [http://hdl.handle.net/10807/27410]
Association between glomerular filtration rate and adverse drug reactions in elderly hospitalized patients: the role of the estimating equation
Pedone, Claudio;Onder, Graziano;Antonelli Incalzi, Raffaele
2011
Abstract
Reduced renal function increases the risk of adverse drug reactions (ADRs) to hydrosoluble drugs (hADRs). However, the ability of different equations to calculate estimated glomerular filtration rate (eGFR) or estimated creatinine clearance (eCCr) and thereby predict the risk of developing hADRs has not previously been compared.
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