BACKGROUND: Traumatic brain injury (TBI) is going to be the third-leading cause of death worldwide, according to the WHO. Two european surveys suggested that adherence to brain trauma guidelines is poor. No study has compared compliance between low- (LMICs) and high-income (UHICs) countries. Hence, this study aimed to investigate differences in the management of severe TBI patients, comparing low- and high-income, and adherence to the BTF guidelines. METHODS: a web-based survey was spread through the global Neuro foundation, different neurosurgical societies, and social media. RESULTS: a total of 803 neurosurgeons participated: 70.4 from UHICs and 29.6% from LMICs. Hypertonic was administered as an early measure by the 73% and 65% of the responders in LMICs and UHICs, respectively (P=0.016). an invasive intracranial pressure monitoring was recommended by the 66% and 58% of the neurosurgeons in LMICs and UHICs, respectively (P<0.001). antiseizure drugs (P<0.001) were given most frequently in LMICs as, against recommendations, steroids (87% vs. 61% and 86% vs. 81%, respectively). in the LMICs both the evacuation of the contusion and decompressive craniectomy were performed earlier than in UHICs (30% vs. 17% with P<0.001 and 44% vs. 28% with P=0.006, respectively). In the LMICs, the head CT control was performed mostly between 12 and 24 hours from the first imaging (38% vs. 23%, P<0.001). CONCLUSIONS: The current Guidelines on TBI do not always fit to both the resources and circumstances in different countries. Future research and clinical practice guidelines should reflect the greater relevance of TBI in low resource settings.
Saraceno, G., Servadei, F., Di Bergamo, L. T., Iaccarino, C., Rubiano, A. M., Zoia, C., De Bonis, P., Raffa, G., Hawryluk, G., Grotenhuis, A., Demetriades, A. K., Sala, F., Belotti, F., Zanin, L., Doglietto, F., Panciani, P. P., Biroli, A., Agosti, E., Serioli, S., Rasulic, L., Bruneau, M., Germano, I. M., Bosnjak, R., Thome, C., Regli, L., Vukic, M., Tessitore, E., Schaller, K., Chaurasia, B., El-Ghandour, N. M. F., Di Ieva, A., Bongetta, D., Borghesi, I., Fazio, M., Esene, I. N., Rosseau, G., El Abbadi, N., Baccanelli, M., Vajkoczy, P., Fontanella, M. M., Do neurosurgeons follow the guidelines? A world-based survey on severe traumatic brain injury, <<JOURNAL OF NEUROSURGICAL SCIENCES>>, 2021; 65 (5): 465-473. [doi:10.23736/S0390-5616.21.05475-8] [https://hdl.handle.net/10807/268776]
Do neurosurgeons follow the guidelines? A world-based survey on severe traumatic brain injury
Doglietto, Francesco;Fontanella, Marco Maria
2021
Abstract
BACKGROUND: Traumatic brain injury (TBI) is going to be the third-leading cause of death worldwide, according to the WHO. Two european surveys suggested that adherence to brain trauma guidelines is poor. No study has compared compliance between low- (LMICs) and high-income (UHICs) countries. Hence, this study aimed to investigate differences in the management of severe TBI patients, comparing low- and high-income, and adherence to the BTF guidelines. METHODS: a web-based survey was spread through the global Neuro foundation, different neurosurgical societies, and social media. RESULTS: a total of 803 neurosurgeons participated: 70.4 from UHICs and 29.6% from LMICs. Hypertonic was administered as an early measure by the 73% and 65% of the responders in LMICs and UHICs, respectively (P=0.016). an invasive intracranial pressure monitoring was recommended by the 66% and 58% of the neurosurgeons in LMICs and UHICs, respectively (P<0.001). antiseizure drugs (P<0.001) were given most frequently in LMICs as, against recommendations, steroids (87% vs. 61% and 86% vs. 81%, respectively). in the LMICs both the evacuation of the contusion and decompressive craniectomy were performed earlier than in UHICs (30% vs. 17% with P<0.001 and 44% vs. 28% with P=0.006, respectively). In the LMICs, the head CT control was performed mostly between 12 and 24 hours from the first imaging (38% vs. 23%, P<0.001). CONCLUSIONS: The current Guidelines on TBI do not always fit to both the resources and circumstances in different countries. Future research and clinical practice guidelines should reflect the greater relevance of TBI in low resource settings.
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