INTRODUCTION: We assessed the prevalence and clinical outcomes of segmental colitis associated with diverticulosis (SCAD) in patients with newly diagnosed diverticulosis.METHODS: A 3-year international, multicenter, prospective cohort study was conducted involving 2,215 patients.RESULTS: SCAD diagnosis was posed in 44 patients (30 male patients; median age: 64.5 years; prevalence of 1.99%, 95% confidence interval, 1.45%-2.66%). Patients with SCAD types D and B showed worse symptoms, higher fecal calprotectin values, needed more steroids, and reached less likely complete remission.DISCUSSION: Although SCAD generally had a benign outcome, types B and D were associated with more severe symptoms and worse clinical course.[GRAPHICS].

Tursi, A., Piovani, D., Brandimarte, G., Di Mario, F., Elisei, W., Picchio, M., Allegretta, L., Annunziata, M. L., Bafutto, M., Bassotti, G., Bianco, M. A., Colucci, R., Conigliaro, R., Dumitrascu, D. L., Escalante, R., Ferrini, L., Forti, G., Franceschi, M., Graziani, M. G., Lammert, F., Latella, G., Maconi, G., Compare, D., Nardone, G., Camara De Castro Oliveira, L., Chaves Oliveira, E., Papagrigoriadis, S., Pietrzak, A., Pontone, S., Stundiene, I., Pranzo, G., Reichert, M. C., Rodinò, S., Regula, J., Scaccianoce, G., Scaldaferri, F., Vassallo, R., Zampaletta, C., Zullo, A., Spaziani, E., Bonovas, S., Papa, A., Danese, S., Null, N., Prevalence and Natural History of Segmental Colitis Associated With Diverticulosis, <<THE AMERICAN JOURNAL OF GASTROENTEROLOGY>>, 2023; 118 (11): 2088-2092. [doi:10.14309/ajg.0000000000002362] [https://hdl.handle.net/10807/268423]

Prevalence and Natural History of Segmental Colitis Associated With Diverticulosis

Tursi, Antonio;Scaldaferri, Franco;Papa, Alfredo;
2023

Abstract

INTRODUCTION: We assessed the prevalence and clinical outcomes of segmental colitis associated with diverticulosis (SCAD) in patients with newly diagnosed diverticulosis.METHODS: A 3-year international, multicenter, prospective cohort study was conducted involving 2,215 patients.RESULTS: SCAD diagnosis was posed in 44 patients (30 male patients; median age: 64.5 years; prevalence of 1.99%, 95% confidence interval, 1.45%-2.66%). Patients with SCAD types D and B showed worse symptoms, higher fecal calprotectin values, needed more steroids, and reached less likely complete remission.DISCUSSION: Although SCAD generally had a benign outcome, types B and D were associated with more severe symptoms and worse clinical course.[GRAPHICS].
2023
Inglese
Tursi, A., Piovani, D., Brandimarte, G., Di Mario, F., Elisei, W., Picchio, M., Allegretta, L., Annunziata, M. L., Bafutto, M., Bassotti, G., Bianco, M. A., Colucci, R., Conigliaro, R., Dumitrascu, D. L., Escalante, R., Ferrini, L., Forti, G., Franceschi, M., Graziani, M. G., Lammert, F., Latella, G., Maconi, G., Compare, D., Nardone, G., Camara De Castro Oliveira, L., Chaves Oliveira, E., Papagrigoriadis, S., Pietrzak, A., Pontone, S., Stundiene, I., Pranzo, G., Reichert, M. C., Rodinò, S., Regula, J., Scaccianoce, G., Scaldaferri, F., Vassallo, R., Zampaletta, C., Zullo, A., Spaziani, E., Bonovas, S., Papa, A., Danese, S., Null, N., Prevalence and Natural History of Segmental Colitis Associated With Diverticulosis, <<THE AMERICAN JOURNAL OF GASTROENTEROLOGY>>, 2023; 118 (11): 2088-2092. [doi:10.14309/ajg.0000000000002362] [https://hdl.handle.net/10807/268423]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/268423
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