Fine-needle aspiration biopsy (FNAB) is the most reliable diagnostic tool in the diagnosis of thyroid nodules. A cytologic diagnosis of follicular neoplasm with atypical cells of undetermined significance (FN/AUS) implies that the selection of patients between surgery and follow-up is difficult. In this setting immunocytochemical stainings might be helpful. The efficacy of a panel made up of HBME-1 and Galectin-3 antibodies is evaluated in cases processed by liquid-based cytology (LBC).
Fadda, G., Rossi, E., Raffaelli, M., Pontecorvi, A., Sioletic, S., Morassi, F., Lombardi, C. P., Zannoni, G., Rindi, G., Follicular thyroid neoplasms can be classified as low- and high-risk according to HBME-1 and Galectin-3 expression on liquid-based fine-needle cytology, <<EUROPEAN JOURNAL OF ENDOCRINOLOGY>>, 2011; 165 (3): 447-453. [doi:10.1530/EJE-11-0181] [http://hdl.handle.net/10807/2658]
Follicular thyroid neoplasms can be classified as low- and high-risk according to HBME-1 and Galectin-3 expression on liquid-based fine-needle cytology
Fadda, Guido;Raffaelli, Marco;Pontecorvi, Alfredo;Sioletic, Stefano;Morassi, Francesca;Lombardi, Celestino Pio;Rindi, Guido
2011
Abstract
Fine-needle aspiration biopsy (FNAB) is the most reliable diagnostic tool in the diagnosis of thyroid nodules. A cytologic diagnosis of follicular neoplasm with atypical cells of undetermined significance (FN/AUS) implies that the selection of patients between surgery and follow-up is difficult. In this setting immunocytochemical stainings might be helpful. The efficacy of a panel made up of HBME-1 and Galectin-3 antibodies is evaluated in cases processed by liquid-based cytology (LBC).
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