Fine-needle aspiration biopsy (FNAB) is the most reliable diagnostic tool in the diagnosis of thyroid nodules. A cytologic diagnosis of follicular neoplasm with atypical cells of undetermined significance (FN/AUS) implies that the selection of patients between surgery and follow-up is difficult. In this setting immunocytochemical stainings might be helpful. The efficacy of a panel made up of HBME-1 and Galectin-3 antibodies is evaluated in cases processed by liquid-based cytology (LBC).
Fadda, G., Rossi, E., Raffaelli, M., Pontecorvi, A., Sioletic, S., Morassi, F., Lombardi, C. P., Zannoni, G., Rindi, G., Follicular thyroid neoplasms can be classified as low- and high-risk according to HBME-1 and Galectin-3 expression on liquid-based fine-needle cytology, <<EUROPEAN JOURNAL OF ENDOCRINOLOGY>>, 2011; 165 (3): 447-453. [doi:10.1530/EJE-11-0181] [http://hdl.handle.net/10807/2658]
Autori: | |
Titolo: | Follicular thyroid neoplasms can be classified as low- and high-risk according to HBME-1 and Galectin-3 expression on liquid-based fine-needle cytology |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1530/EJE-11-0181 |
Data di pubblicazione: | 2011 |
Abstract: | Fine-needle aspiration biopsy (FNAB) is the most reliable diagnostic tool in the diagnosis of thyroid nodules. A cytologic diagnosis of follicular neoplasm with atypical cells of undetermined significance (FN/AUS) implies that the selection of patients between surgery and follow-up is difficult. In this setting immunocytochemical stainings might be helpful. The efficacy of a panel made up of HBME-1 and Galectin-3 antibodies is evaluated in cases processed by liquid-based cytology (LBC). |
Lingua: | Inglese |
Rivista: | |
Citazione: | Fadda, G., Rossi, E., Raffaelli, M., Pontecorvi, A., Sioletic, S., Morassi, F., Lombardi, C. P., Zannoni, G., Rindi, G., Follicular thyroid neoplasms can be classified as low- and high-risk according to HBME-1 and Galectin-3 expression on liquid-based fine-needle cytology, <<EUROPEAN JOURNAL OF ENDOCRINOLOGY>>, 2011; 165 (3): 447-453. [doi:10.1530/EJE-11-0181] [http://hdl.handle.net/10807/2658] |
Appare nelle tipologie: | Articolo in rivista, Nota a sentenza |