Oligometastatic colorectal cancer (CRC) is a clinically relevant entity, and surgery is the gold standard therapeutic option. Current guidelines recommend evaluating other local ablative treatments (LATs) in patients not eligible for surgery. Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) and stereotactic body radiation therapy (SBRT) are emerging as highly beneficial less-invasive LATs in alternative to surgery. In our paper, we report the first case in literature of lymph node metastases from CRC treated sequentially with EUS-RFA and SBRT, providing evidence of their efficacy and safety. LATs combined with systemic chemotherapy might be included in a multimodal therapeutic approach to oligometastatic disease.

Borrelli De Andreis, F., Calegari, M. A., Romano, A., Brizi, M. G., Sofo, L., Boskoski, I., Costamagna, G., Attili, F., Combination of endoscopic ultrasound-guided radiofrequency ablation and adaptive radiation therapy for the treatment of lymph node metastases from colon adenocarcinoma: A case report, <<CURRENT PROBLEMS IN CANCER. CASE REPORTS>>, 2023; 9 (march): N/A-N/A. [doi:10.1016/j.cpccr.2023.100216] [https://hdl.handle.net/10807/265334]

Combination of endoscopic ultrasound-guided radiofrequency ablation and adaptive radiation therapy for the treatment of lymph node metastases from colon adenocarcinoma: A case report

Borrelli De Andreis, Federica;Calegari, Maria Alessandra;Romano, Angela;Brizi, Maria Gabriella;Sofo, Luigi;Boskoski, Ivo;Costamagna, Guido;Attili, Fabia
2023

Abstract

Oligometastatic colorectal cancer (CRC) is a clinically relevant entity, and surgery is the gold standard therapeutic option. Current guidelines recommend evaluating other local ablative treatments (LATs) in patients not eligible for surgery. Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) and stereotactic body radiation therapy (SBRT) are emerging as highly beneficial less-invasive LATs in alternative to surgery. In our paper, we report the first case in literature of lymph node metastases from CRC treated sequentially with EUS-RFA and SBRT, providing evidence of their efficacy and safety. LATs combined with systemic chemotherapy might be included in a multimodal therapeutic approach to oligometastatic disease.
2023
Inglese
Borrelli De Andreis, F., Calegari, M. A., Romano, A., Brizi, M. G., Sofo, L., Boskoski, I., Costamagna, G., Attili, F., Combination of endoscopic ultrasound-guided radiofrequency ablation and adaptive radiation therapy for the treatment of lymph node metastases from colon adenocarcinoma: A case report, <<CURRENT PROBLEMS IN CANCER. CASE REPORTS>>, 2023; 9 (march): N/A-N/A. [doi:10.1016/j.cpccr.2023.100216] [https://hdl.handle.net/10807/265334]
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