Unlabelled: Large seasonal outbreaks of bronchiolitis put pressure on healthcare systems and particularly on intensive care units (ICUs). ICU admission is necessary to provide respiratory support to the severest cases, otherwise bronchiolitis can result in substantial mortality. ICU resources are often insufficient and there is scant evidence to guide the ICU clinical management. Most available studies do not cover the ICU-admitted cases and do not consider the associated public health issues. We review this topic through a multidisciplinary approach from both the clinical and public health perspectives, with an analysis based on pathophysiology and cost-effectiveness. We suggest ways to optimise respiratory care, minimise ICU stay, "protect" ICU beds and, whenever possible, make them available for other critically ill children. We also provide guidance on how to prepare ICUs to work under stressful conditions due to outbreaks and to reduce the risk of nosocomial cross-contamination, particularly in ICUs caring for high-risk children. Funding: None.

De Luca, D., Pezza, L., Vivalda, L., Di Nardo, M., Lepainteur, M., Baraldi, E., Piastra, M., Ricciardi, W., Conti, G., Gualano, M. R., Critical care of severe bronchiolitis during shortage of ICU resources, <<ECLINICALMEDICINE>>, 2024; 69 (N/A): N/A-N/A. [doi:10.1016/j.eclinm.2024.102450] [https://hdl.handle.net/10807/262681]

Critical care of severe bronchiolitis during shortage of ICU resources

Piastra, Marco;Ricciardi, Walter;Conti, Giorgio;
2024

Abstract

Unlabelled: Large seasonal outbreaks of bronchiolitis put pressure on healthcare systems and particularly on intensive care units (ICUs). ICU admission is necessary to provide respiratory support to the severest cases, otherwise bronchiolitis can result in substantial mortality. ICU resources are often insufficient and there is scant evidence to guide the ICU clinical management. Most available studies do not cover the ICU-admitted cases and do not consider the associated public health issues. We review this topic through a multidisciplinary approach from both the clinical and public health perspectives, with an analysis based on pathophysiology and cost-effectiveness. We suggest ways to optimise respiratory care, minimise ICU stay, "protect" ICU beds and, whenever possible, make them available for other critically ill children. We also provide guidance on how to prepare ICUs to work under stressful conditions due to outbreaks and to reduce the risk of nosocomial cross-contamination, particularly in ICUs caring for high-risk children. Funding: None.
2024
Inglese
De Luca, D., Pezza, L., Vivalda, L., Di Nardo, M., Lepainteur, M., Baraldi, E., Piastra, M., Ricciardi, W., Conti, G., Gualano, M. R., Critical care of severe bronchiolitis during shortage of ICU resources, <<ECLINICALMEDICINE>>, 2024; 69 (N/A): N/A-N/A. [doi:10.1016/j.eclinm.2024.102450] [https://hdl.handle.net/10807/262681]
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