We report two young girls, the first almost 18 years old and the second 121/2 years old, affected with nonspecific interstitial pneumonia, both diagnosed at the age of 11 by open lung biopsy and both being treated with low-dose steroid. Due to insufficient response to conventional therapy and based on positive therapeutic results following the use of subcutaneous recombinant interferon gamma-1b in fibrosing interstitial pneumonias of adults, they were given a 1-year trial of subcutaneous recombinant interferon gamma-1b in association with a steroid. Our experience with these two young patients suggests that interferon gamma-1b cannot be considered as stabilizing or a curative therapy to control or reverse nonspecific interstitial pneumonia unresponsive to steroids alone. © The Mount Sinai Journal of Medicine.

Rigante, D., Delogu, A. B., Federico, G., De Rosa, G., Stabile, A., Recombinant interferon Gamma-lb and low-dose steroid in two pediatric cases of nonspecific interstitial pneumonia, <<MOUNT SINAI JOURNAL OF MEDICINE>>, 2004; 71 (2): 139-142 [https://hdl.handle.net/10807/257420]

Recombinant interferon Gamma-lb and low-dose steroid in two pediatric cases of nonspecific interstitial pneumonia

Rigante, Donato;Delogu, Angelica Bibiana;De Rosa, Gabriella;
2004

Abstract

We report two young girls, the first almost 18 years old and the second 121/2 years old, affected with nonspecific interstitial pneumonia, both diagnosed at the age of 11 by open lung biopsy and both being treated with low-dose steroid. Due to insufficient response to conventional therapy and based on positive therapeutic results following the use of subcutaneous recombinant interferon gamma-1b in fibrosing interstitial pneumonias of adults, they were given a 1-year trial of subcutaneous recombinant interferon gamma-1b in association with a steroid. Our experience with these two young patients suggests that interferon gamma-1b cannot be considered as stabilizing or a curative therapy to control or reverse nonspecific interstitial pneumonia unresponsive to steroids alone. © The Mount Sinai Journal of Medicine.
2004
Inglese
Rigante, D., Delogu, A. B., Federico, G., De Rosa, G., Stabile, A., Recombinant interferon Gamma-lb and low-dose steroid in two pediatric cases of nonspecific interstitial pneumonia, <<MOUNT SINAI JOURNAL OF MEDICINE>>, 2004; 71 (2): 139-142 [https://hdl.handle.net/10807/257420]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/257420
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