Purpose: Obesity and pregnancy are strictly related: on the one hand, obesity—one of the most common comorbidities in women of reproductive age—contributes to infertility and obesity-related pregnancy complications, whereas pregnancy is a condition in which, physiologically, the pregnant woman undergoes weight gain. Endoscopic sleeve gastroplasty (ESG) may be used for the treatment of obesity in women of childbearing age. Materials and Methods: A retrospective analysis was conducted to evaluate weight trajectories, the evolution of obesity-related comorbidities, and lifestyle modification in women who became pregnant after ESG. A comparison was made between childbearing-age women who became pregnant after ESG and non-pregnant women. Results: A total of 150 childbearing-age women underwent ESG at a large tertiary medical center. Of these, 11 patients (33.4 ± 6.2 years) became pregnant after the procedure, following a mean time interval of 5.5 ± 3.9 months. Three women (two affected by polycystic ovary syndrome) reported difficulty getting pregnant before undergoing ESG. The mean preconception BMI was 31.9±4.0 kg/m2 (−7.24 ± 4.0 kg/m2 after ESG). Total body weight loss (TBWL, %) was 18.08 ± 8.00, 11.00 ± 11.08, and 12.08 ± 8.49, at the beginning of pregnancy, at the delivery, and at the first follow-up (19.6 ± 7.8 months after ESG). TBWL of at least 5% was achieved before pregnancy in all patients (73% reached a TBWL ≥ 10%). No significant differences in weight loss and QoL were found between the pregnancy and non-pregnancy groups up to 24 months after ESG. Conclusions: Endoscopic sleeve gastroplasty allows for adequate weight loss before and after pregnancy in patients with obesity. Graphical Abstract: [Figure not available: see fulltext.]

Carlino, G., Benson, A. A., Bove, V., Pontecorvi, V., De Siena, M., Matteo, M. V., Farina, A., Polidori, G., Vinti, L., Giannetti, G., Costamagna, G., Spada, C., Boskoski, I., Impact of Pregnancy on Weight Loss After Endoscopic Sleeve Gastroplasty, <<OBESITY SURGERY>>, 2023; 33 (10): 3097-3105. [doi:10.1007/s11695-023-06745-6] [https://hdl.handle.net/10807/250871]

Impact of Pregnancy on Weight Loss After Endoscopic Sleeve Gastroplasty

Carlino, Giorgio;Bove, Vincenzo;Pontecorvi, Valerio;De Siena, Martina;Matteo, Maria Valeria;Giannetti, Giulia;Costamagna, Guido;Spada, Cristiano;Boskoski, Ivo
2023

Abstract

Purpose: Obesity and pregnancy are strictly related: on the one hand, obesity—one of the most common comorbidities in women of reproductive age—contributes to infertility and obesity-related pregnancy complications, whereas pregnancy is a condition in which, physiologically, the pregnant woman undergoes weight gain. Endoscopic sleeve gastroplasty (ESG) may be used for the treatment of obesity in women of childbearing age. Materials and Methods: A retrospective analysis was conducted to evaluate weight trajectories, the evolution of obesity-related comorbidities, and lifestyle modification in women who became pregnant after ESG. A comparison was made between childbearing-age women who became pregnant after ESG and non-pregnant women. Results: A total of 150 childbearing-age women underwent ESG at a large tertiary medical center. Of these, 11 patients (33.4 ± 6.2 years) became pregnant after the procedure, following a mean time interval of 5.5 ± 3.9 months. Three women (two affected by polycystic ovary syndrome) reported difficulty getting pregnant before undergoing ESG. The mean preconception BMI was 31.9±4.0 kg/m2 (−7.24 ± 4.0 kg/m2 after ESG). Total body weight loss (TBWL, %) was 18.08 ± 8.00, 11.00 ± 11.08, and 12.08 ± 8.49, at the beginning of pregnancy, at the delivery, and at the first follow-up (19.6 ± 7.8 months after ESG). TBWL of at least 5% was achieved before pregnancy in all patients (73% reached a TBWL ≥ 10%). No significant differences in weight loss and QoL were found between the pregnancy and non-pregnancy groups up to 24 months after ESG. Conclusions: Endoscopic sleeve gastroplasty allows for adequate weight loss before and after pregnancy in patients with obesity. Graphical Abstract: [Figure not available: see fulltext.]
2023
Inglese
Carlino, G., Benson, A. A., Bove, V., Pontecorvi, V., De Siena, M., Matteo, M. V., Farina, A., Polidori, G., Vinti, L., Giannetti, G., Costamagna, G., Spada, C., Boskoski, I., Impact of Pregnancy on Weight Loss After Endoscopic Sleeve Gastroplasty, <<OBESITY SURGERY>>, 2023; 33 (10): 3097-3105. [doi:10.1007/s11695-023-06745-6] [https://hdl.handle.net/10807/250871]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/250871
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