A recent meta-analysis has indicated that, in patients with dementia, the use of atypical antipsychotics is associated with an excess mortality. Later observational studies have suggested that conventional antipsychotics may pose an even greater risk of death. None of these studies could evaluate the risk associated with single antipsychotics nor could they provide any conclusive evidence concerning the risk among nursing home residents. We conducted a retrospective cohort study to compare the risk of death associated with atypical and conventional antipsychotics in a large population of nursing home residents with dementia.

Liperoti, R., Onder, G., Landi, F. L., Lapane, K., Mor, V., Bernabei, R., Gambassi, G., All-cause mortality associated with atypical and conventional antipsychotics among nursing home residents with dementia: a retrospective cohort study, <<JOURNAL OF CLINICAL PSYCHIATRY>>, 2009; 70 (10): 1340-1347. [doi:10.4088/JCP.08m04597yel] [http://hdl.handle.net/10807/24909]

All-cause mortality associated with atypical and conventional antipsychotics among nursing home residents with dementia: a retrospective cohort study

Liperoti, Rosa;Onder, Graziano;Landi, Francesco Luigi;Bernabei, Roberto;Gambassi, Giovanni
2009

Abstract

A recent meta-analysis has indicated that, in patients with dementia, the use of atypical antipsychotics is associated with an excess mortality. Later observational studies have suggested that conventional antipsychotics may pose an even greater risk of death. None of these studies could evaluate the risk associated with single antipsychotics nor could they provide any conclusive evidence concerning the risk among nursing home residents. We conducted a retrospective cohort study to compare the risk of death associated with atypical and conventional antipsychotics in a large population of nursing home residents with dementia.
Inglese
Liperoti, R., Onder, G., Landi, F. L., Lapane, K., Mor, V., Bernabei, R., Gambassi, G., All-cause mortality associated with atypical and conventional antipsychotics among nursing home residents with dementia: a retrospective cohort study, <<JOURNAL OF CLINICAL PSYCHIATRY>>, 2009; 70 (10): 1340-1347. [doi:10.4088/JCP.08m04597yel] [http://hdl.handle.net/10807/24909]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/24909
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