: Sarcopenia is a geriatric condition characterized by a progressive loss of skeletal muscle mass and strength, with an increased risk of adverse health outcomes (e.g., falls, disability, institutionalization, reduced quality of life, mortality). Pharmacological remedies are currently unavailable for preventing the development of sarcopenia, halting its progression, or impeding its negative health outcomes. The most effective strategies to contrast sarcopenia rely on the adoption of healthier lifestyle behaviors, including adherence to high-quality diets and regular physical activity. In this review, the role of nutrition in the prevention and management of sarcopenia is summarized. Special attention is given to current "blockbuster" dietary regimes and agents used to counteract age-related muscle wasting, together with their putative mechanisms of action. Issues related to the design and implementation of effective nutritional strategies are discussed, with a focus on unanswered questions on the most appropriate timing of nutritional interventions to preserve muscle health and function into old age. A brief description is also provided on new technologies that can facilitate the development and implementation of personalized nutrition plans to contrast sarcopenia.

Calvani, R., Picca, A., Coelho-Júnior, H. J., Tosato, M., Marzetti, E., Landi, F., Diet for the prevention and management of sarcopenia, <<METABOLISM, CLINICAL AND EXPERIMENTAL>>, 2023; 146 (September): 1-16. [doi:10.1016/j.metabol.2023.155637] [https://hdl.handle.net/10807/240695]

Diet for the prevention and management of sarcopenia

Calvani, Riccardo
Primo
;
Tosato, Matteo;Marzetti, Emanuele
Penultimo
;
Landi, Francesco
Ultimo
2023

Abstract

: Sarcopenia is a geriatric condition characterized by a progressive loss of skeletal muscle mass and strength, with an increased risk of adverse health outcomes (e.g., falls, disability, institutionalization, reduced quality of life, mortality). Pharmacological remedies are currently unavailable for preventing the development of sarcopenia, halting its progression, or impeding its negative health outcomes. The most effective strategies to contrast sarcopenia rely on the adoption of healthier lifestyle behaviors, including adherence to high-quality diets and regular physical activity. In this review, the role of nutrition in the prevention and management of sarcopenia is summarized. Special attention is given to current "blockbuster" dietary regimes and agents used to counteract age-related muscle wasting, together with their putative mechanisms of action. Issues related to the design and implementation of effective nutritional strategies are discussed, with a focus on unanswered questions on the most appropriate timing of nutritional interventions to preserve muscle health and function into old age. A brief description is also provided on new technologies that can facilitate the development and implementation of personalized nutrition plans to contrast sarcopenia.
2023
Inglese
Calvani, R., Picca, A., Coelho-Júnior, H. J., Tosato, M., Marzetti, E., Landi, F., Diet for the prevention and management of sarcopenia, <<METABOLISM, CLINICAL AND EXPERIMENTAL>>, 2023; 146 (September): 1-16. [doi:10.1016/j.metabol.2023.155637] [https://hdl.handle.net/10807/240695]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/240695
Citazioni
  • ???jsp.display-item.citation.pmc??? 6
  • Scopus 10
  • ???jsp.display-item.citation.isi??? 12
social impact