ABSTRACT:INTRODUCTION: We describe three different fetal or neonatal outcomes in the offspring of a mother who had persistent circulating thyrotropin receptor antibodies despite having undergone a total thyroidectomy several years before. CASE PRESENTATION: The three different outcomes were an intrauterine death, a mild and transient fetal and neonatal hyperthyroidism and a severe fetal and neonatal hyperthyroidism that required specific therapy. CONCLUSIONS: The three cases are interesting because of the different outcomes, the absence of a direct correlation between thyrotropin receptor antibody levels and clinical signs, and the persistence of thyrotropin receptor antibodies several years after a total thyroidectomy.

Zuppa, A. A., Sindico, P., Perrone, S., Carducci, C., Antichi, E., Alighieri, G., Cota, F., Papacci, P., De Carolis, M. P., Romagnoli, C., Cardiello, V., Different fetal-neonatal outcomes in siblings born to a mother with Graves-Basedow disease after total thyroidectomy: a case series., <<JOURNAL OF MEDICAL CASE REPORTS>>, 2010; (Febbraio): 59-62 [http://hdl.handle.net/10807/23141]

Different fetal-neonatal outcomes in siblings born to a mother with Graves-Basedow disease after total thyroidectomy: a case series.

Zuppa;Antonio Alberto; Sindico;S.; Carducci;Chiara; Antichi;Eleonora; Alighieri;Giovanni; Cota;Francesco; Papacci;Patrizia; De Carolis;Maria Pia; Romagnoli;Costantino; Cardiello
2010

Abstract

ABSTRACT:INTRODUCTION: We describe three different fetal or neonatal outcomes in the offspring of a mother who had persistent circulating thyrotropin receptor antibodies despite having undergone a total thyroidectomy several years before. CASE PRESENTATION: The three different outcomes were an intrauterine death, a mild and transient fetal and neonatal hyperthyroidism and a severe fetal and neonatal hyperthyroidism that required specific therapy. CONCLUSIONS: The three cases are interesting because of the different outcomes, the absence of a direct correlation between thyrotropin receptor antibody levels and clinical signs, and the persistence of thyrotropin receptor antibodies several years after a total thyroidectomy.
Inglese
Zuppa, A. A., Sindico, P., Perrone, S., Carducci, C., Antichi, E., Alighieri, G., Cota, F., Papacci, P., De Carolis, M. P., Romagnoli, C., Cardiello, V., Different fetal-neonatal outcomes in siblings born to a mother with Graves-Basedow disease after total thyroidectomy: a case series., <<JOURNAL OF MEDICAL CASE REPORTS>>, 2010; (Febbraio): 59-62 [http://hdl.handle.net/10807/23141]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/23141
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