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EnglishABSTRACT:INTRODUCTION: We describe three different fetal or neonatal outcomes in the offspring of a mother who had persistent circulating thyrotropin receptor antibodies despite having undergone a total thyroidectomy several years before. CASE PRESENTATION: The three different outcomes were an intrauterine death, a mild and transient fetal and neonatal hyperthyroidism and a severe fetal and neonatal hyperthyroidism that required specific therapy. CONCLUSIONS: The three cases are interesting because of the different outcomes, the absence of a direct correlation between thyrotropin receptor antibody levels and clinical signs, and the persistence of thyrotropin receptor antibodies several years after a total thyroidectomy.
Zuppa, A. A., Sindico, P., Perrone, S., Carducci, C., Antichi, E., Alighieri, G., Cota, F., Papacci, P., De Carolis, M. P., Romagnoli, C., Cardiello, V., Different fetal-neonatal outcomes in siblings born to a mother with Graves-Basedow disease after total thyroidectomy: a case series., <<JOURNAL OF MEDICAL CASE REPORTS>>, 2010; (Febbraio): 59-62 [http://hdl.handle.net/10807/23141]
| Autori: | |
| Titolo: | Different fetal-neonatal outcomes in siblings born to a mother with Graves-Basedow disease after total thyroidectomy: a case series. |
| Data di pubblicazione: | 2010 |
| Abstract: | ABSTRACT:INTRODUCTION: We describe three different fetal or neonatal outcomes in the offspring of a mother who had persistent circulating thyrotropin receptor antibodies despite having undergone a total thyroidectomy several years before. CASE PRESENTATION: The three different outcomes were an intrauterine death, a mild and transient fetal and neonatal hyperthyroidism and a severe fetal and neonatal hyperthyroidism that required specific therapy. CONCLUSIONS: The three cases are interesting because of the different outcomes, the absence of a direct correlation between thyrotropin receptor antibody levels and clinical signs, and the persistence of thyrotropin receptor antibodies several years after a total thyroidectomy. |
| Lingua: | Inglese |
| Rivista: | |
| Citazione: | Zuppa, A. A., Sindico, P., Perrone, S., Carducci, C., Antichi, E., Alighieri, G., Cota, F., Papacci, P., De Carolis, M. P., Romagnoli, C., Cardiello, V., Different fetal-neonatal outcomes in siblings born to a mother with Graves-Basedow disease after total thyroidectomy: a case series., <<JOURNAL OF MEDICAL CASE REPORTS>>, 2010; (Febbraio): 59-62 [http://hdl.handle.net/10807/23141] |
| Appare nelle tipologie: | Articolo in rivista, Nota a sentenza |
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