The human gut microbiome (GM) is a complex ecosystem that includes numerous prokaryotic and eukaryotic inhabitants. The composition of GM can influence an array of host physiological functions including immune development. Accumulating evidence suggest that several members of non-bacterial microbiota, including protozoa and helminths, that were earlier considered as pathogens, could have a commensal or beneficial relationship with the host. Here we examine the most recent data from omics studies on prokaryota-meiofauna-host interaction as well as the impact of gut parasitome on gut bacterial ecology and its role as 'immunological driver' in health and disease to glimpse new therapeutic perspectives.
Ianiro, G., Iorio, A., Porcari, S., Masucci, L., Sanguinetti, M., Perno, C. F., Gasbarrini, A., Putignani, L., Cammarota, G., How the gut parasitome affects human health, <<THERAPEUTIC ADVANCES IN GASTROENTEROLOGY>>, N/A; 15 (N/A): 17562848221091524-N/A. [doi:10.1177/17562848221091524] [https://hdl.handle.net/10807/230851]
How the gut parasitome affects human health
Ianiro, Gianluca;Porcari, Serena;Masucci, Luca;Sanguinetti, Maurizio;Gasbarrini, Antonio;Putignani, Lorenza;Cammarota, Giovanni
2022
Abstract
The human gut microbiome (GM) is a complex ecosystem that includes numerous prokaryotic and eukaryotic inhabitants. The composition of GM can influence an array of host physiological functions including immune development. Accumulating evidence suggest that several members of non-bacterial microbiota, including protozoa and helminths, that were earlier considered as pathogens, could have a commensal or beneficial relationship with the host. Here we examine the most recent data from omics studies on prokaryota-meiofauna-host interaction as well as the impact of gut parasitome on gut bacterial ecology and its role as 'immunological driver' in health and disease to glimpse new therapeutic perspectives.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
