PURPOSE: To assess pregnancy and neonatal outcomes in a woman accidentally exposed to Verteporfin photodynamic therapy in the third week of pregnancy. METHODS: Post-conception counselling and prospective follow-up by telephone interview at Telefono Rosso (Teratology Information Service) were carried out. The baby was examined at birth and at 26 months. RESULTS: The outcome of the pregnancy was normal and a healthy female child with a normal birthweight was born. The baby's follow-up was normal at 26 months. CONCLUSIONS: This is the first reported case of a childbearing woman being accidentally exposed to Verteporfin during pregnancy. No fetal or neonatal adverse effects were documented.
De Santis, M., Carducci, B., De Santis, L., Lucchese, A., Straface, G., First case of post-conception Verteporfin exposure: pregnancy and neonatal outcome., <<ACTA OPHTHALMOLOGICA SCANDINAVICA>>, 2004; (Ottobre): 623-624 [http://hdl.handle.net/10807/22665]
First case of post-conception Verteporfin exposure: pregnancy and neonatal outcome.
De Santis, Marco;Carducci, Brigida;
2004
Abstract
PURPOSE: To assess pregnancy and neonatal outcomes in a woman accidentally exposed to Verteporfin photodynamic therapy in the third week of pregnancy. METHODS: Post-conception counselling and prospective follow-up by telephone interview at Telefono Rosso (Teratology Information Service) were carried out. The baby was examined at birth and at 26 months. RESULTS: The outcome of the pregnancy was normal and a healthy female child with a normal birthweight was born. The baby's follow-up was normal at 26 months. CONCLUSIONS: This is the first reported case of a childbearing woman being accidentally exposed to Verteporfin during pregnancy. No fetal or neonatal adverse effects were documented.
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