Chronic inflammation and subsequent tissutal alterations may play a key role in prostate carcinogenesis. In this way, molecular alterations of the suppressor of cytokine signaling 3 (SOCS3), one of the most important inhibitory molecule of inflammatory signal transduction circuitries, could contribute to explain the pleiotropic role of interleukin-6 (IL-6) in this type of cancer.

Pierconti, F., Martini, M., Pinto, F., Cenci, T., Capodimonti, S., Calarco, A., Bassi, P., Larocca, L. M., Epigenetic silencing of SOCS3 identifies a subset of prostate cancer with an aggressive behavior, <<THE PROSTATE>>, 2011; 71 (3): 318-325. [doi:10.1002/pros.21245] [http://hdl.handle.net/10807/2251]

Epigenetic silencing of SOCS3 identifies a subset of prostate cancer with an aggressive behavior

Pierconti, Francesco;Pinto, Francesco;Cenci, Tonia;Capodimonti, Sara;Calarco, Alessandro;Bassi, Pierfrancesco;Larocca, Luigi Maria
2011

Abstract

Chronic inflammation and subsequent tissutal alterations may play a key role in prostate carcinogenesis. In this way, molecular alterations of the suppressor of cytokine signaling 3 (SOCS3), one of the most important inhibitory molecule of inflammatory signal transduction circuitries, could contribute to explain the pleiotropic role of interleukin-6 (IL-6) in this type of cancer.
2011
Inglese
Pierconti, F., Martini, M., Pinto, F., Cenci, T., Capodimonti, S., Calarco, A., Bassi, P., Larocca, L. M., Epigenetic silencing of SOCS3 identifies a subset of prostate cancer with an aggressive behavior, <<THE PROSTATE>>, 2011; 71 (3): 318-325. [doi:10.1002/pros.21245] [http://hdl.handle.net/10807/2251]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/2251
Citazioni
  • ???jsp.display-item.citation.pmc??? 39
  • Scopus 67
  • ???jsp.display-item.citation.isi??? 59
social impact