OBJECTIVE: Small Bowel Obstruction (SBO) is a common emergency in older patients. The most appropriate treatment strategy is still matter of debate. The aim of this study was to compare a non-operative management (NOM) vs. a surgical procedure for patients >= 80 years with SBO. PATIENTS AND METHODS: All patients >= 80 years admitted to our Emergency Department (ED) for SBO between January 1st, 2015, and December 31st, 2020 were included in this study. In order to correct for baseline covariates and factors associated to clinical management, we used a 1:1 propensity score matching (PSM) analysis. The primary outcome was to compare the over-all in-hospital mortality. Secondary outcomes included occurrence of major complications and in-hospital length of stay (LOS). RESULTS: A total of 561 patients were en-rolled. After propensity score matching (PSM) analysis, 302 patients (151 each group) were included in the analysis. Mortality did not differ between the two groups. After PSM mechanical ventilation, sepsis, cumulative major complications, and LOS were significantly higher in the operative treatment group [15.9% vs. 1.5%, 9.4% vs. 4.1%, 27.6% vs. 19.2%, and 9.4 (6.4-14.3) days vs. 8.1 (4.5-13.3) days, respectively; p < 0.001, p=0.013, p=0.025, and p=0.003, respectively]. CONCLUSIONS: In patients >= 80 years with SBO, a NOM could yield similar results, in terms of overall mortality, compared to a surgical management. Thus, particularly in patients with multiple comorbidities or functional impairments, a conservative approach should always be considered.

Rosa, F., Covino, M., Fransvea, P., Quero, G., Pacini, G., Fiorillo, C., Simeoni, B., La Greca, A., Sganga, G., Franceschi, F., Gasbarrini, A., Alfieri, S., Management of Small Bowel Obstruction (SBO) in older adults (>80 years): a propensity score-matched analysis on predictive factors for a (un)successful non-operative management (NOM), <<EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES>>, 2022; 26 (19): 7219-7228. [doi:10.26355/eurrev_202210_29914] [https://hdl.handle.net/10807/223391]

Management of Small Bowel Obstruction (SBO) in older adults (>80 years): a propensity score-matched analysis on predictive factors for a (un)successful non-operative management (NOM)

Rosa, Fausto
;
Covino, Marcello;Fransvea, Pietro;Quero, Giuseppe;Pacini, Giovanni;Fiorillo, Claudio;La Greca, Antonio;Sganga, Gabriele;Franceschi, Francesco;Gasbarrini, Antonio;Alfieri, Sergio
2022

Abstract

OBJECTIVE: Small Bowel Obstruction (SBO) is a common emergency in older patients. The most appropriate treatment strategy is still matter of debate. The aim of this study was to compare a non-operative management (NOM) vs. a surgical procedure for patients >= 80 years with SBO. PATIENTS AND METHODS: All patients >= 80 years admitted to our Emergency Department (ED) for SBO between January 1st, 2015, and December 31st, 2020 were included in this study. In order to correct for baseline covariates and factors associated to clinical management, we used a 1:1 propensity score matching (PSM) analysis. The primary outcome was to compare the over-all in-hospital mortality. Secondary outcomes included occurrence of major complications and in-hospital length of stay (LOS). RESULTS: A total of 561 patients were en-rolled. After propensity score matching (PSM) analysis, 302 patients (151 each group) were included in the analysis. Mortality did not differ between the two groups. After PSM mechanical ventilation, sepsis, cumulative major complications, and LOS were significantly higher in the operative treatment group [15.9% vs. 1.5%, 9.4% vs. 4.1%, 27.6% vs. 19.2%, and 9.4 (6.4-14.3) days vs. 8.1 (4.5-13.3) days, respectively; p < 0.001, p=0.013, p=0.025, and p=0.003, respectively]. CONCLUSIONS: In patients >= 80 years with SBO, a NOM could yield similar results, in terms of overall mortality, compared to a surgical management. Thus, particularly in patients with multiple comorbidities or functional impairments, a conservative approach should always be considered.
Inglese
Rosa, F., Covino, M., Fransvea, P., Quero, G., Pacini, G., Fiorillo, C., Simeoni, B., La Greca, A., Sganga, G., Franceschi, F., Gasbarrini, A., Alfieri, S., Management of Small Bowel Obstruction (SBO) in older adults (>80 years): a propensity score-matched analysis on predictive factors for a (un)successful non-operative management (NOM), <<EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES>>, 2022; 26 (19): 7219-7228. [doi:10.26355/eurrev_202210_29914] [https://hdl.handle.net/10807/223391]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/223391
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