Purpose: The complexity of multimodal approaches in cancer management has lately led to the establishment of multidisciplinary tumor boards (MDTBs) to define targeted, patient-centered treatment strategies. However, few data are available regarding the application of this approach in Ocular Oncology. Hereby, the Authors analyze the implementation and outcomes of a trained MDTB in a tertiary ocular oncology referral center. Methods: A retrospective descriptive analysis of MDTB meetings discussing patients with ocular and periocular cancers, over a 12-months period, was carried out. Data were grouped by main site involved, topics discussed and final clinical decisions therefore taken. Meetings were held by a constant 'Core team' or - when required - by a broader 'Extended team'. Results: During the observational period 86 cases were discussed. In 27 patients ocular surface tissues were involved (31%), in 25 patients orbital tissues (29%), in 22 patients eyelids (26%), and in 12 patients intraocular tissues (14%). In 13 cases (15%) naïve or referred new patients, in 34 cases (40%) imaging or histopathologic reports and in 39 cases (45%) treatment plans were discussed. Regarding final decisions, a treatment plan was scheduled in 47 cases (55%) and a diagnostic ascertainment was required in 27 patients (31%); locally advanced and/or systemic diseases were referred or teamed up with other specialists in 12 cases (14%). Conclusions: Ocular Oncology multidisciplinary team, by sharing expertise of different specialists, ensures a comprehensive evaluation of patients improving the accuracy of diagnosis and staging upon which planning a proper treatment. Further studies are needed to assess if this approach may also improve the outcomes and prognosis of patients.

Savino, G., Piccinni, F., Pagliara, M. M., Sammarco, M. G., Caputo, C. G., Moro, A., Barbera, G., Tagliaferri, L., Fionda, B., Schinzari, G., Rossi, E., Zagaria, L., Peris, K., Di Stefani, A., Musarra, T., Ausili Cefaro, L., Martucci, M., Blasi, M. A., Multidisciplinary ocular and periocular cancers meetings: implementation in a tertiary referral center and analysis over a 12-months period, <<BMC OPHTHALMOLOGY>>, 2022; 22 (1): 497-506. [doi:10.1186/s12886-022-02694-3] [https://hdl.handle.net/10807/222625]

Multidisciplinary ocular and periocular cancers meetings: implementation in a tertiary referral center and analysis over a 12-months period

Savino, Gustavo;Piccinni, Fabrizio;Pagliara, Monica Maria;Sammarco, Maria Grazia;Caputo, Carmela Grazia;Moro, Alessandro;Barbera, Giorgio;Tagliaferri, Luca;Schinzari, Giovanni;Rossi, Ernesto;Zagaria, Luca;Peris, Ketty;Di Stefani, Alessandro;Ausili Cefaro, Luca;Martucci, Matia;Blasi, Maria Antonietta
2022

Abstract

Purpose: The complexity of multimodal approaches in cancer management has lately led to the establishment of multidisciplinary tumor boards (MDTBs) to define targeted, patient-centered treatment strategies. However, few data are available regarding the application of this approach in Ocular Oncology. Hereby, the Authors analyze the implementation and outcomes of a trained MDTB in a tertiary ocular oncology referral center. Methods: A retrospective descriptive analysis of MDTB meetings discussing patients with ocular and periocular cancers, over a 12-months period, was carried out. Data were grouped by main site involved, topics discussed and final clinical decisions therefore taken. Meetings were held by a constant 'Core team' or - when required - by a broader 'Extended team'. Results: During the observational period 86 cases were discussed. In 27 patients ocular surface tissues were involved (31%), in 25 patients orbital tissues (29%), in 22 patients eyelids (26%), and in 12 patients intraocular tissues (14%). In 13 cases (15%) naïve or referred new patients, in 34 cases (40%) imaging or histopathologic reports and in 39 cases (45%) treatment plans were discussed. Regarding final decisions, a treatment plan was scheduled in 47 cases (55%) and a diagnostic ascertainment was required in 27 patients (31%); locally advanced and/or systemic diseases were referred or teamed up with other specialists in 12 cases (14%). Conclusions: Ocular Oncology multidisciplinary team, by sharing expertise of different specialists, ensures a comprehensive evaluation of patients improving the accuracy of diagnosis and staging upon which planning a proper treatment. Further studies are needed to assess if this approach may also improve the outcomes and prognosis of patients.
Inglese
Savino, G., Piccinni, F., Pagliara, M. M., Sammarco, M. G., Caputo, C. G., Moro, A., Barbera, G., Tagliaferri, L., Fionda, B., Schinzari, G., Rossi, E., Zagaria, L., Peris, K., Di Stefani, A., Musarra, T., Ausili Cefaro, L., Martucci, M., Blasi, M. A., Multidisciplinary ocular and periocular cancers meetings: implementation in a tertiary referral center and analysis over a 12-months period, <<BMC OPHTHALMOLOGY>>, 2022; 22 (1): 497-506. [doi:10.1186/s12886-022-02694-3] [https://hdl.handle.net/10807/222625]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/222625
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