Despite the relatively low number of studies and the presence of methodological limitations, available evidence suggests long COVID negatively impacts muscle health and QoL. These sequelae may be amplified in older adults due to preexisting agerelated declines in muscle health. Acute and long-term assessments of these parameters are needed to optimize patient care. The mechanisms by which long COVID impacts muscle health are multifactorial and involve a combination of systemic inflammation, physical inactivity, poor nutritional status, and inadequate dietary intake. Other factors such as age, comorbidities, and degree of disease severity may also contribute to negative musculoskeletal outcomes during long COVID.Overall, the evidence to date suggests long COVID negatively impacts body composition, muscle function, and QoL. Recovery and rehabilitation services with adequate nutrition, mental and social support should be explored as potential multimodal interventions to improve muscle health of these patients.
Montes-Ibarra, M., Oliveira, C. L. P., Orsso, C. E., Landi, F., Marzetti, E., Prado, C. M., The Impact of Long COVID-19 on Muscle Health, <<CLINICS IN GERIATRIC MEDICINE>>, 2022; 38 (3): 545-557. [doi:10.1016/j.cger.2022.03.004] [https://hdl.handle.net/10807/220346]
The Impact of Long COVID-19 on Muscle Health
Landi, Francesco;Marzetti, Emanuele;
2022
Abstract
Despite the relatively low number of studies and the presence of methodological limitations, available evidence suggests long COVID negatively impacts muscle health and QoL. These sequelae may be amplified in older adults due to preexisting agerelated declines in muscle health. Acute and long-term assessments of these parameters are needed to optimize patient care. The mechanisms by which long COVID impacts muscle health are multifactorial and involve a combination of systemic inflammation, physical inactivity, poor nutritional status, and inadequate dietary intake. Other factors such as age, comorbidities, and degree of disease severity may also contribute to negative musculoskeletal outcomes during long COVID.Overall, the evidence to date suggests long COVID negatively impacts body composition, muscle function, and QoL. Recovery and rehabilitation services with adequate nutrition, mental and social support should be explored as potential multimodal interventions to improve muscle health of these patients.
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