Purpose of Review: Summarize the writings published in the last 5 years on the management of surgery in the first line of treatment for advanced ovarian cancer. Recent Findings: For patients with a significant tumor burden, the neoadjuvant chemotherapy therapy (NACT) with interval debulking surgery (IDS) strategy shows comparable efficacy than primary debulking surgery (PDS) in terms of survival in randomized studies with less morbidity. Summary: Advanced epithelial ovarian cancer generates more than half cases a recurrence. First-line treatment is based on a chemotherapy regimen combining a platinum-based and a taxane-based, associated with surgery. This review considers papers of last 5 years of timing, thinking tools, and innovation in the management. The choice of strategy, PDS or IDS, would be a personalized recommendation. The challenge is to adapt the timing of the surgery to the patient’s characteristics and that of her disease.

Hudry, D., Becourt, S., Scambia, G., Fagotti, A., Primary or Interval Debulking Surgery in Advanced Ovarian Cancer: a Personalized Decision—a Literature Review, <<CURRENT ONCOLOGY REPORTS>>, 2022; (N/A): N/A-N/A. [doi:10.1007/s11912-022-01318-9] [https://hdl.handle.net/10807/220106]

Primary or Interval Debulking Surgery in Advanced Ovarian Cancer: a Personalized Decision—a Literature Review

Scambia, G.;Fagotti, A.
2022

Abstract

Purpose of Review: Summarize the writings published in the last 5 years on the management of surgery in the first line of treatment for advanced ovarian cancer. Recent Findings: For patients with a significant tumor burden, the neoadjuvant chemotherapy therapy (NACT) with interval debulking surgery (IDS) strategy shows comparable efficacy than primary debulking surgery (PDS) in terms of survival in randomized studies with less morbidity. Summary: Advanced epithelial ovarian cancer generates more than half cases a recurrence. First-line treatment is based on a chemotherapy regimen combining a platinum-based and a taxane-based, associated with surgery. This review considers papers of last 5 years of timing, thinking tools, and innovation in the management. The choice of strategy, PDS or IDS, would be a personalized recommendation. The challenge is to adapt the timing of the surgery to the patient’s characteristics and that of her disease.
Inglese
Hudry, D., Becourt, S., Scambia, G., Fagotti, A., Primary or Interval Debulking Surgery in Advanced Ovarian Cancer: a Personalized Decision—a Literature Review, <<CURRENT ONCOLOGY REPORTS>>, 2022; (N/A): N/A-N/A. [doi:10.1007/s11912-022-01318-9] [https://hdl.handle.net/10807/220106]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/220106
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