IRIS PubliCatt
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EnglishBACKGROUND: Gadolinium derivatives are ionic paramagnetic contrast agents used to enhance magnetic resonance images, labeled as a pregnancy category C by the Food and Drug Administration because of a lack of epidemiological studies concerning first-trimester exposure. METHODS: Prospective cohort study to determine whether gadolinium derivatives exposure in periconceptional period is a risk factor for pregnancy or fetal development. RESULTS: We report the outcome of 26 pregnant women exposed to gadolinium derivatives in the first trimester without adverse effect on pregnancy and neonatal outcome. CONCLUSIONS: Currently, this study represents the only prospective investigation of gadolinium derivatives in pregnancy, but more data are necessary to exclude a teratogenic risk.
De Santis, M., Straface, G., Cavaliere, A. F., Carducci, B., Caruso, A., Gadolinium Periconceptional exposure: pregnancy and neonatal outcome., <<ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA>>, 2007; (86 (1)): 99-101 [http://hdl.handle.net/10807/21974]
| Autori: | |
| Titolo: | Gadolinium Periconceptional exposure: pregnancy and neonatal outcome. |
| Data di pubblicazione: | 2007 |
| Abstract: | BACKGROUND: Gadolinium derivatives are ionic paramagnetic contrast agents used to enhance magnetic resonance images, labeled as a pregnancy category C by the Food and Drug Administration because of a lack of epidemiological studies concerning first-trimester exposure. METHODS: Prospective cohort study to determine whether gadolinium derivatives exposure in periconceptional period is a risk factor for pregnancy or fetal development. RESULTS: We report the outcome of 26 pregnant women exposed to gadolinium derivatives in the first trimester without adverse effect on pregnancy and neonatal outcome. CONCLUSIONS: Currently, this study represents the only prospective investigation of gadolinium derivatives in pregnancy, but more data are necessary to exclude a teratogenic risk. |
| Lingua: | Inglese |
| Rivista: | |
| Citazione: | De Santis, M., Straface, G., Cavaliere, A. F., Carducci, B., Caruso, A., Gadolinium Periconceptional exposure: pregnancy and neonatal outcome., <<ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA>>, 2007; (86 (1)): 99-101 [http://hdl.handle.net/10807/21974] |
| Appare nelle tipologie: | Articolo in rivista, Nota a sentenza |
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