predicting the outcome for patients with myelofibrosis undergoingi an allogenic hemopoietic stem cell transplant

Several predictive scores have been described for patients with myelofibrosis (MF): these include IPSS [1], DIPPS [2], MYSEC [3], MIPSS [4] and GIPSS [5]. All of these have in common the identification of clinical, and biological risk factors for evolution of the disease and death. When these prognostic scores are applied to patients undergoing a hemopoietic stem cell transplant (HSCT), the outcome reflects the progression of the disease: patients with an early disease, always do better than patients with more advanced disease, and/or a higher risk score