In the expedition Gokyo Khumbu/Ama Dablam Trek 2012, we studied the effects of two 12-day training periods performed both at sea level and at high altitude. The main results on adult women have been published in six original articles. In women, high altitude trekking induced CD69 T cell activation and promoted anti-stress effects of the immune responses and the oxidative balance (1). Low-to-moderate exercise training at s.l. improves the regenerative capacity of skeletal muscle and depicted the epigenetic signature of satellite cells. The cell differentiation was favored by increased [Ca2+]i and fusion index (2). On the contrary, the training in hypobaric-hypoxia induced oxidative stress and impaired the regenerative capacity of satellite cells (6). Although training did not significantly modify muscle phenotype , it induced beneficial adaptations of the oxygen transport-utilization systems witnessed by faster VO2 kinetics at exercise onset (3). The two training periods did not influence the postural stability (4). In young adult women, micturition physiological parameters were affected during adaptation to hypoxia; the correlation with SpO2 strongly suggests a role of hypoxia in these changes (5)

18., C. C., Aloisi, A., Bruseghini, P., Calabria, E., Caprara, G., Catizone, A., Dal Sacco, L., Di Filippo, E., Di Giulio, C., Doria, C., Fulle, S., Grassi, B., Lanuti, P., Mancinelli, R., Marchisio, M., Mariggiò, M., Morabito, C., Paulesu, L., Pietrangelo, T., Pogliaghi, S., Reggiani, C., Ricci, G., Rotini, A., Salvadego, D., Schena, F., Scordella, A., Tam, E., Toniolo, L., Vernillo, G., Verratti, V., Fanò-Illic, G., Gokyo Khumbu/Ama Dablam Trek 2012, Abstract de <<67th National Congress of the Italian Physiological Society>>, (Catania, 21-23 September 2016 ), Società Italaina Fisiologia, Catania, Italy 2016: 200-200 [http://hdl.handle.net/10807/215543]

Gokyo Khumbu/Ama Dablam Trek 2012

Bruseghini, P;
2016

Abstract

In the expedition Gokyo Khumbu/Ama Dablam Trek 2012, we studied the effects of two 12-day training periods performed both at sea level and at high altitude. The main results on adult women have been published in six original articles. In women, high altitude trekking induced CD69 T cell activation and promoted anti-stress effects of the immune responses and the oxidative balance (1). Low-to-moderate exercise training at s.l. improves the regenerative capacity of skeletal muscle and depicted the epigenetic signature of satellite cells. The cell differentiation was favored by increased [Ca2+]i and fusion index (2). On the contrary, the training in hypobaric-hypoxia induced oxidative stress and impaired the regenerative capacity of satellite cells (6). Although training did not significantly modify muscle phenotype , it induced beneficial adaptations of the oxygen transport-utilization systems witnessed by faster VO2 kinetics at exercise onset (3). The two training periods did not influence the postural stability (4). In young adult women, micturition physiological parameters were affected during adaptation to hypoxia; the correlation with SpO2 strongly suggests a role of hypoxia in these changes (5)
Inglese
Book of abstract
67th National Congress of the Italian Physiological Society
Catania
21-set-2016
23-set-2016
n/a
Società Italaina Fisiologia
18., C. C., Aloisi, A., Bruseghini, P., Calabria, E., Caprara, G., Catizone, A., Dal Sacco, L., Di Filippo, E., Di Giulio, C., Doria, C., Fulle, S., Grassi, B., Lanuti, P., Mancinelli, R., Marchisio, M., Mariggiò, M., Morabito, C., Paulesu, L., Pietrangelo, T., Pogliaghi, S., Reggiani, C., Ricci, G., Rotini, A., Salvadego, D., Schena, F., Scordella, A., Tam, E., Toniolo, L., Vernillo, G., Verratti, V., Fanò-Illic, G., Gokyo Khumbu/Ama Dablam Trek 2012, Abstract de <<67th National Congress of the Italian Physiological Society>>, (Catania, 21-23 September 2016 ), Società Italaina Fisiologia, Catania, Italy 2016: 200-200 [http://hdl.handle.net/10807/215543]
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