The association between maternal celiac disease (CD) and both reduced fertility and increased risk of adverse pregnancy-related events has been long documented. However, no evidences are available regarding the pathogenic mechanisms of this link. The aim of this study was to determine whether anti-tissue transglutaminase (anti-tTG) antibodies are involved in the damage of trophoblastic cells in vitro.
Di Simone, N., Silano, M., Castellani, R., Di Nicuolo, F., D'Alessio, M., Franceschi, F., Tritarelli, A., Leone, A. M., Tersigni, C., Gasbarrini, G. B., Silveri, N., Caruso, A., Gasbarrini, A., Anti-tissue transglutaminase antibodies from celiac patients are responsible for trophoblast damage via apoptosis in vitro, <<THE AMERICAN JOURNAL OF GASTROENTEROLOGY>>, 2010; 105 (10): 2254-2261. [doi:10.1038/ajg.2010.233] [http://hdl.handle.net/10807/21486]
Anti-tissue transglutaminase antibodies from celiac patients are responsible for trophoblast damage via apoptosis in vitro
Di Simone, Nicoletta;Franceschi, Francesco;Leone, Antonio Maria;Tersigni, Chiara;Gasbarrini, Giovanni Battista;Gasbarrini, Antonio
2010
Abstract
The association between maternal celiac disease (CD) and both reduced fertility and increased risk of adverse pregnancy-related events has been long documented. However, no evidences are available regarding the pathogenic mechanisms of this link. The aim of this study was to determine whether anti-tissue transglutaminase (anti-tTG) antibodies are involved in the damage of trophoblastic cells in vitro.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
