Pr5-ALA has been well-established for use in intraoperative fluorescence-guided resection of malignant glioma. It is not as strongly supported for use with low-grade gliomas (LGG) because only a few of these, less than 20%, have visible porphyrin accumulation, which is useful for 5-ALA-guided surgery. We report here our experience with 5-ALA uptake in a case of suspected relapse of anaplastic oligodendroglioma, IDH-mutant and 1p/19q-codeleted.
La Rocca, G., Barresi, V., Sabatino, G., Altieri, R., Ius, T., Olivi, A., Mazzucchi, E., Pignotti, F., Della Pepa, G. M., 5-ALA False-Positive in Anaplastic Oligodendroglioma, IDH-mutant and 1p/19q-codeleted, <<SURGICAL TECHNOLOGY INTERNATIONAL>>, 2020; 36 (maggio): 453-456 [http://hdl.handle.net/10807/206797]
5-ALA False-Positive in Anaplastic Oligodendroglioma, IDH-mutant and 1p/19q-codeleted
La Rocca, Giuseppe;Sabatino, Giovanni;Olivi, Alessandro;Mazzucchi, Edoardo;Pignotti, Fabrizio;Della Pepa, Giuseppe Maria
2020
Abstract
Pr5-ALA has been well-established for use in intraoperative fluorescence-guided resection of malignant glioma. It is not as strongly supported for use with low-grade gliomas (LGG) because only a few of these, less than 20%, have visible porphyrin accumulation, which is useful for 5-ALA-guided surgery. We report here our experience with 5-ALA uptake in a case of suspected relapse of anaplastic oligodendroglioma, IDH-mutant and 1p/19q-codeleted.
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