Invasiveness in pituitary adenomas has been defined and investigated from multiple perspectives, with varying results when its predictive value is considered. A systematic literature review, following PRISMA guidelines, was performed, searching PubMed and Scopus databases with terms that included molecular markers, histological, radiological, anatomical and surgical data on invasiveness of pituitary adenomas. The results showed that differing views are still present for anatomical aspects of the sellar region that are relevant to the concept of invasiveness; radiological and histological diagnoses are still limited, but might improve in the future, especially if they are related to surgical findings, which have become more accurate thanks to the introduction of the endoscope. The aim is to achieve a correct distinction between truly invasive pituitary adenomas from those that, in contrast, present with extension in the parasellar area through natural pathways. At present, diagnosis of invasiveness should be based on a comprehensive analysis of radiological, intraoperative and histological findings.

Serioli, S., Doglietto, F., Fiorindi, A., Biroli, A., Mattavelli, D., Buffoli, B., Ferrari, M., Cornali, C., Rodella, L., Maroldi, R., Gasparotti, R., Nicolai, P., Maria Fontanella, M., Luigi Poliani, P., Pituitary adenomas and invasiveness from anatomo-surgical, radiological, and histological perspectives: A systematic literature review, <<CANCERS>>, 2019; 11 (12): 1936-1957. [doi:10.3390/cancers11121936] [http://hdl.handle.net/10807/206557]

Pituitary adenomas and invasiveness from anatomo-surgical, radiological, and histological perspectives: A systematic literature review

Doglietto, F.
Co-primo
;
2019

Abstract

Invasiveness in pituitary adenomas has been defined and investigated from multiple perspectives, with varying results when its predictive value is considered. A systematic literature review, following PRISMA guidelines, was performed, searching PubMed and Scopus databases with terms that included molecular markers, histological, radiological, anatomical and surgical data on invasiveness of pituitary adenomas. The results showed that differing views are still present for anatomical aspects of the sellar region that are relevant to the concept of invasiveness; radiological and histological diagnoses are still limited, but might improve in the future, especially if they are related to surgical findings, which have become more accurate thanks to the introduction of the endoscope. The aim is to achieve a correct distinction between truly invasive pituitary adenomas from those that, in contrast, present with extension in the parasellar area through natural pathways. At present, diagnosis of invasiveness should be based on a comprehensive analysis of radiological, intraoperative and histological findings.
Inglese
Serioli, S., Doglietto, F., Fiorindi, A., Biroli, A., Mattavelli, D., Buffoli, B., Ferrari, M., Cornali, C., Rodella, L., Maroldi, R., Gasparotti, R., Nicolai, P., Maria Fontanella, M., Luigi Poliani, P., Pituitary adenomas and invasiveness from anatomo-surgical, radiological, and histological perspectives: A systematic literature review, <<CANCERS>>, 2019; 11 (12): 1936-1957. [doi:10.3390/cancers11121936] [http://hdl.handle.net/10807/206557]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/206557
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 21
  • ???jsp.display-item.citation.isi??? 24
social impact